Layered titanates with fibrous nanotopographic features as reservoir for bioactive ions to enhance osteogenesis.
文献类型：期刊论文
| 作者 | Yate, Luis; Gregurec, Danijela; Tang, Wei; Song, Xiaoxia; Wang, Guocheng; Moya, Sergio Enrique |
| 刊名 | APPLIED SURFACE SCIENCE
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | In this study, an osteogenic environment was constructed on Ti alloy implants by in-situ formation of nanosized fibrous titanate, Na2Ti6O13, loaded withbioactive ions, i.e. Sr, Mg and Zn, to enhance surface bioactivity. The bioactive ions were loaded by ion exchange with sodium located at inter-layer positions between the TiO6 slabs, and their release was not associated with the degradation of the structural unit of the titanate. In-vitro cell culture experiments using MC3T3-E1 cells proved that both bioactive ions and nanotopographic features are critical in promoting osteogenic differentiation of the cells. It was found that the osteogenic functions of the titanate can be modulated by the type and amount of ions incorporated. This study points out that nanosized fibrous titanate formed on the Ti alloy can be a promising reservoir for bioactive ions. The major advantage of this approach over other alternatives forbioactive ion delivery using degradable bioceramic coatings is its capacity of maintaining the structural integrity of the coating and thus avoiding structural deterioration and potential mechanical failure. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14706]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 推荐引用方式 GB/T 7714 | Yate, Luis,Gregurec, Danijela,Tang, Wei,et al. Layered titanates with fibrous nanotopographic features as reservoir for bioactive ions to enhance osteogenesis.[J]. APPLIED SURFACE SCIENCE,2018. |
| APA | Yate, Luis,Gregurec, Danijela,Tang, Wei,Song, Xiaoxia,Wang, Guocheng,&Moya, Sergio Enrique.(2018).Layered titanates with fibrous nanotopographic features as reservoir for bioactive ions to enhance osteogenesis..APPLIED SURFACE SCIENCE. |
| MLA | Yate, Luis,et al."Layered titanates with fibrous nanotopographic features as reservoir for bioactive ions to enhance osteogenesis.".APPLIED SURFACE SCIENCE (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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