A unique hybrid-structured surface produced by rapid electrochemical anodization enhances bio-corrosion resistance and bone cell responses of beta-type Ti-24Nb-4Zr-8Sn alloy.
文献类型：期刊论文
| 作者 | Hou, Wen-Tao; Liu, Jeng-Fen; Lee, Tzu-Hsin; Liu, Chia-Fei; Huang, Her-Hsiung; Pan, Haobo; Hao, Yu-Lin; Li, Shu-Jun |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Ti-24Nb-4Zr-8Sn (Ti2448), a new beta-type Ti alloy, consists of nontoxic elements and exhibits a low uniaxial tensile elastic modulus of approximately 45 GPa for biomedical implant applications. Nevertheless, the bio-corrosion resistance and biocompatibility of Ti2448 alloys must be improved for long-term clinical use. In this study, a rapid electrochemical anodization treatment was used on Ti2448 alloys to enhance the bio-corrosion resistance and bone cell responsesby altering the surface characteristics. The proposed anodization process produces a unique hybrid oxide layer (thickness 50-120 nm) comprising amesoporous outer section and a dense inner section. Experiment results show that the dense inner section enhances the bio-corrosion resistance. Moreover, the mesoporous surface topography, which is on a similar scale as various biological species, improves the wettability, protein adsorption, focal adhesion complex formation and bone cell differentiation. Outside-in signals can be triggered through the interaction of integrins with the mesoporous topography to form the focal adhesion complex and to further induce osteogenic differentiation pathway. These results demonstrate that the proposed electrochemicalanodization process for Ti2448 alloys with a low uniaxial tensile elastic modulus has the potential for biomedical implant applications. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14711]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 推荐引用方式 GB/T 7714 | Hou, Wen-Tao,Liu, Jeng-Fen,Lee, Tzu-Hsin,et al. A unique hybrid-structured surface produced by rapid electrochemical anodization enhances bio-corrosion resistance and bone cell responses of beta-type Ti-24Nb-4Zr-8Sn alloy.[J]. SCIENTIFIC REPORTS,2018. |
| APA | Hou, Wen-Tao.,Liu, Jeng-Fen.,Lee, Tzu-Hsin.,Liu, Chia-Fei.,Huang, Her-Hsiung.,...&Li, Shu-Jun.(2018).A unique hybrid-structured surface produced by rapid electrochemical anodization enhances bio-corrosion resistance and bone cell responses of beta-type Ti-24Nb-4Zr-8Sn alloy..SCIENTIFIC REPORTS. |
| MLA | Hou, Wen-Tao,et al."A unique hybrid-structured surface produced by rapid electrochemical anodization enhances bio-corrosion resistance and bone cell responses of beta-type Ti-24Nb-4Zr-8Sn alloy.".SCIENTIFIC REPORTS (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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