Evolution of pallium, hippocampus,and cortical cell types revealed by single-cell transcriptomics in reptiles
文献类型：期刊论文
| 作者 | Georgi Tushev; Maria Antonietta Tosches; Tracy M. Yamawaki; Robert K. Naumann; Ariel A. Jacobi; Gilles Laurent |
| 刊名 | Science
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Computations in the mammalian cortex are carried out by glutamatergic and γ-aminobutyric acid–releasing (GABAergic) neurons forming specialized circuits and areas. Here we asked how these neurons and areas evolved in amniotes. We built a gene expression atlas of the pallium of two reptilian species using large-scale single-cell messenger RNA sequencing. The transcriptomic signature of glutamatergic neurons in reptilian cortex suggests that mammalian neocortical layers are made of new cell types generated by diversification of ancestral gene-regulatory programs. By contrast, the diversity of reptilian cortical GABAergic neurons indicates that the interneuron classes known in mammals already existed in the common ancestor of all amniotes. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/13867]  |
| 专题 | 深圳先进技术研究院_脑所 |
| 推荐引用方式 GB/T 7714 | Georgi Tushev,Maria Antonietta Tosches,Tracy M. Yamawaki,et al. Evolution of pallium, hippocampus,and cortical cell types revealed by single-cell transcriptomics in reptiles[J]. Science,2018. |
| APA | Georgi Tushev,Maria Antonietta Tosches,Tracy M. Yamawaki,Robert K. Naumann,Ariel A. Jacobi,&Gilles Laurent.(2018).Evolution of pallium, hippocampus,and cortical cell types revealed by single-cell transcriptomics in reptiles.Science. |
| MLA | Georgi Tushev,et al."Evolution of pallium, hippocampus,and cortical cell types revealed by single-cell transcriptomics in reptiles".Science (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。