Effects of Ketamine on Basal Gamma Band Oscillation and Sensory Gating in Prefrontal Cortex of Awake Rats
文献类型：期刊论文
| 作者 | Chen, Nanhui; Geng, Xin; Wu, Xujun; Li, Jinghui; Qi, Renli; Yu, Hualin |
| 刊名 | NEUROSCIENCE BULLETIN
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Gamma band oscillation (GBO) and sensory gating (SG) are associated with many cognitive functions. Ketamine induces deficits of GBO and SG in the prefrontal cortex (PFC). However, the time-courses of the effects of different doses of ketamine on GBO power and SG are poorly understood. Studies have indicated that GBO power and SG have a common substrate for their generation and abnormalities. In this study, we found that (1) ketamine administration increased GBO power in the PFC in rats differently in the low- and high-dose groups; (2) auditory SG was significantly lower than baseline in the 30 mg/kg and 60 mg/kg groups, but not in the 15 mg/kg and 120 mg/kg groups; and (3) changes in SG and basal GBO power were significantly correlated in awake rats. These results indicate a relationship between mechanisms underlying auditory SG and GBO power. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/13870]  |
| 专题 | 深圳先进技术研究院_脑所 |
| 推荐引用方式 GB/T 7714 | Chen, Nanhui,Geng, Xin,Wu, Xujun,et al. Effects of Ketamine on Basal Gamma Band Oscillation and Sensory Gating in Prefrontal Cortex of Awake Rats[J]. NEUROSCIENCE BULLETIN,2018. |
| APA | Chen, Nanhui,Geng, Xin,Wu, Xujun,Li, Jinghui,Qi, Renli,&Yu, Hualin.(2018).Effects of Ketamine on Basal Gamma Band Oscillation and Sensory Gating in Prefrontal Cortex of Awake Rats.NEUROSCIENCE BULLETIN. |
| MLA | Chen, Nanhui,et al."Effects of Ketamine on Basal Gamma Band Oscillation and Sensory Gating in Prefrontal Cortex of Awake Rats".NEUROSCIENCE BULLETIN (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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