Commodity Chemicals From Engineered Modular Type I Polyketide Synthases
文献类型：期刊论文
| 作者 | Katz,Leonard; Yuzawa, Satoshi; Zargar, Amin; Pang, Bo; Keasling, Jay D |
| 刊名 | Methods in enzymology
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Reduced polyketides are a subclass of natural products that have a variety of medical, veterinary, and agricultural applications and are well known for their structural diversity. Although these compounds do not resemble each other, they are all made by a class of enzymes known as modular polyketide synthases (PKSs). The commonality of PKS domains/modules that compose PKSs and the understanding of the relationship between the sequence of the PKS and the structure of the compound it produces render modular PKSs as excellent targets for engineering to produce novel compounds with predicted structures. Here, we describe experimental protocols and considerations for modular PKS engineering and two case studies to produce commodity chemicals by engineered PKSs. |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/13448]  |
| 专题 | 合成所 |
| 推荐引用方式 GB/T 7714 | Katz,Leonard,Yuzawa, Satoshi,Zargar, Amin,et al. Commodity Chemicals From Engineered Modular Type I Polyketide Synthases[J]. Methods in enzymology,2018. |
| APA | Katz,Leonard,Yuzawa, Satoshi,Zargar, Amin,Pang, Bo,&Keasling, Jay D.(2018).Commodity Chemicals From Engineered Modular Type I Polyketide Synthases.Methods in enzymology. |
| MLA | Katz,Leonard,et al."Commodity Chemicals From Engineered Modular Type I Polyketide Synthases".Methods in enzymology (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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