Revisiting the methionine salvage pathway and itsparalogues
文献类型：期刊论文
| 作者 | Antoine Danchin; Agnieszka Sekowska; Hiroki Ashida |
| 刊名 | Microbial Biotechnology
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Methionine is essential for life. Its chemistry makes it fragile in the presence of oxygen. Aerobic living organisms have selected a salvage pathway (the MSP) that uses dioxygen to regenerate methionine, associated to a ratchet-like step that prevents methionine back degradation. Here, we describe the variation on this theme, developed across the tree of life. Oxygen appeared long after life had developed on Earth. The canonical MSP evolved from ancestors that used both predecessors of ribulose bisphosphate carboxylase oxygenase (RuBisCO) and methanethiol in intermediate steps. We document how these likely promiscuous pathways were also used to metabolize the omnipresent by-products of S-adenosylmethionine radical enzymes as well as the aromatic and isoprene skeleton of quinone electron acceptors |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/13462]  |
| 专题 | 合成所 |
| 推荐引用方式 GB/T 7714 | Antoine Danchin,Agnieszka Sekowska,Hiroki Ashida. Revisiting the methionine salvage pathway and itsparalogues[J]. Microbial Biotechnology,2018. |
| APA | Antoine Danchin,Agnieszka Sekowska,&Hiroki Ashida.(2018).Revisiting the methionine salvage pathway and itsparalogues.Microbial Biotechnology. |
| MLA | Antoine Danchin,et al."Revisiting the methionine salvage pathway and itsparalogues".Microbial Biotechnology (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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