Two new quinolone alkaloids from Dianthus superbus var. superbus
文献类型:期刊论文
作者 | Sun, J (Sun, Jia)[ 1,2 ]; Yu, JH (Yu, Jin-Hai)[ 2 ]; Song, JL (Song, Jia-Li)[ 2 ]; Jiang, CS (Jiang, Cheng-Shi)[ 2 ]; Tao-Yuan (Tao-Yuan)[ 3 ]; Zhang, H (Zhang, Hua)[ 2 ] |
刊名 | TETRAHEDRON LETTERS |
出版日期 | 2019 |
卷号 | 60期号:2页码:161-163 |
ISSN号 | 0040-4039 |
关键词 | Dianthus superbus Quinolone alkaloid ECD calculation Cytoprotection |
DOI | 10.1016/j.tetlet.2018.12.003 |
英文摘要 | Two new quinolone alkaloids, superbusines A (1) and B (2), were obtained from the whole plants of a Chinese medicinal plant, Dianthus superbus var. superbus. Their structures, featuring a glucosyl moiety linked with a rare 2-(hydroxymethyl)-5-(2-hydroxypropan-2-yl)phenol fragment, were determined on the basis of detailed spectroscopic analyses, and the absolute configurations were assigned by time-dependent density functional theory (TD-DFT)-based electronic circular dichroism (ECD) calculations. The two alkaloids were evaluated in a series of bioassays without showing antimicrobial, anti-inflammatory, antioxidant, cytotoxic and alpha-glucosidase inhibitory properties, while they exhibited slight protection against amyloid-beta(A beta)-induced injury on neuron SH-SY5Y cells. |
WOS记录号 | WOS:000456353100016 |
源URL | [http://ir.xjipc.cas.cn/handle/365002/5675] |
专题 | 新疆理化技术研究所_资源化学研究室 |
作者单位 | 1.Univ Jinan, Sch Chem & Chem Engn, 336 West Rd Nan Xinzhuang, Jinan 250022, Shandong, Peoples R China 2.Univ Jinan, Sch Biol Sci & Technol, 336 West Rd Nan Xinzhuang, Jinan 250022, Shandong, Peoples R China 3.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China |
推荐引用方式 GB/T 7714 | Sun, J ,Yu, JH ,Song, JL ,et al. Two new quinolone alkaloids from Dianthus superbus var. superbus[J]. TETRAHEDRON LETTERS,2019,60(2):161-163. |
APA | Sun, J ,Yu, JH ,Song, JL ,Jiang, CS ,Tao-Yuan ,&Zhang, H .(2019).Two new quinolone alkaloids from Dianthus superbus var. superbus.TETRAHEDRON LETTERS,60(2),161-163. |
MLA | Sun, J ,et al."Two new quinolone alkaloids from Dianthus superbus var. superbus".TETRAHEDRON LETTERS 60.2(2019):161-163. |
入库方式: OAI收割
来源:新疆理化技术研究所
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