Preparation of Microgels with Ultrahigh Payload of Various Hydrophilic and Hydrophobic Inorganic Nanoparticle Composites up to 92 wt %
文献类型：期刊论文
| 作者 | Wang, Anhe; Li, Jieling; Dong, Qianqian; Wang, Shengtao; Jian, Honglei; Wang, Meiyue; Ren, Peng; Bai, Shuo |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2019-01-30 |
| 卷号 | 11期号:4页码:4408-4415 |
| 关键词 | microgel encapsulation high payload nanocomposites "casting" strategy |
| ISSN号 | 1944-8244 |
| DOI | 10.1021/acsami.8b20089 |
| 英文摘要 | Microgel loading with inorganic nanoparticle (NP) composites attracts interest for various biomedical applications. However, the encapsulation of NPs into microgels usually is a diffusion process driven by osmotic pressure, which depends highly on the concentration of NPs and causes low loading efficiency. In this work, we demonstrate preparation of microgels with ultrahigh content of various nano-objects (up to 92%, wt %) by a gelatin "casting" strategy using porous CaCO3 particles as templates. This approach could encapsulate various NPs with different charged, hydrophilic, and hydrophobic surfaces, shape, and size within microgels, without causing aggregation or change of physicochemical properties of NPs. The hybrid microgels coupled with properties of both inorganic NPs and hydrogels can be taken as an effective photothermal therapy system with great stability, reusability, and degradability and show high effective photothermal activity which is highly related to the content of NPs within microgels. The strategy of fabrication of microgels with nanocomposites is certified to be simple, facile, and low cost, which has potential applications in cancer therapy, drug delivery, catalysis, detecting system, and sewage treatment. |
| WOS关键词 | GOLD NANOPARTICLES ; CONTROLLED-RELEASE ; HYBRID MICROGELS ; AQUEOUS-MEDIA ; QUANTUM DOTS ; NANORODS ; GELATIN ; GLUCOSE ; MICROCAPSULES ; FABRICATION |
| 资助项目 | National Natural Science Foundation of China[21774132] ; National Natural Science Foundation of China[21703253] |
| WOS研究方向 | Science & Technology - Other Topics ; Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000457816900082 |
| 出版者 | AMER CHEMICAL SOC |
| 资助机构 | National Natural Science Foundation of China |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/27843]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Bai, Shuo |
| 作者单位 | Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Anhe,Li, Jieling,Dong, Qianqian,et al. Preparation of Microgels with Ultrahigh Payload of Various Hydrophilic and Hydrophobic Inorganic Nanoparticle Composites up to 92 wt %[J]. ACS APPLIED MATERIALS & INTERFACES,2019,11(4):4408-4415. |
| APA | Wang, Anhe.,Li, Jieling.,Dong, Qianqian.,Wang, Shengtao.,Jian, Honglei.,...&Bai, Shuo.(2019).Preparation of Microgels with Ultrahigh Payload of Various Hydrophilic and Hydrophobic Inorganic Nanoparticle Composites up to 92 wt %.ACS APPLIED MATERIALS & INTERFACES,11(4),4408-4415. |
| MLA | Wang, Anhe,et al."Preparation of Microgels with Ultrahigh Payload of Various Hydrophilic and Hydrophobic Inorganic Nanoparticle Composites up to 92 wt %".ACS APPLIED MATERIALS & INTERFACES 11.4(2019):4408-4415. |
入库方式： OAI收割
来源：过程工程研究所
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