Role of Resident Stem Cells in Vessel Formation and Arteriosclerosis
文献类型:期刊论文
作者 | Zhang, Li1; Chen, Ting1; Xu, Qingbo1,2; Bhaloo, Shirin Issa2; Zhou, Bin3 |
刊名 | CIRCULATION RESEARCH |
出版日期 | 2018 |
卷号 | 122期号:11页码:1608-1624 |
ISSN号 | 0009-7330 |
关键词 | Smooth-muscle-cells Endothelial Progenitor Cells Fluid Shear-stress American-heart-association Vascular Wall Neointimal Formation Skeletal-muscle In-vitro Definitive Hematopoiesis Atherosclerotic Lesions |
DOI | 10.1161/CIRCRESAHA.118.313058 |
文献子类 | Review |
英文摘要 | Vascular, resident stem cells are present in all 3 layers of the vessel wall; they play a role in vascular formation under physiological conditions and in remodeling in pathological situations. Throughout development and adult early life, resident stem cells participate in vessel formation through vasculogenesis and angiogenesis. In adults, the vascular stem cells are mostly quiescent in their niches but can be activated in response to injury and participate in endothelial repair and smooth muscle cell accumulation to form neointima. However, delineation of the characteristics and of the migration and differentiation behaviors of these stem cells is an area of ongoing investigation. A set of genetic mouse models for cell lineage tracing has been developed to specifically address the nature of these cells and both migration and differentiation processes during physiological angiogenesis and in vascular diseases. This review summarizes the current knowledge on resident stem cells, which has become more defined and refined in vascular biology research, thus contributing to the development of new potential therapeutic strategies to promote endothelial regeneration and ameliorate vascular disease development. |
电子版国际标准刊号 | 1524-4571 |
WOS研究方向 | Cardiac & Cardiovascular Systems ; Hematology ; Peripheral Vascular Disease |
语种 | 英语 |
WOS记录号 | WOS:000435409500018 |
版本 | 出版稿 |
源URL | [http://202.127.25.143/handle/331003/3460] |
专题 | 生化所2018年发文 上海生化细胞研究所_上海生科院生化细胞研究所 |
通讯作者 | Xu, Qingbo |
作者单位 | 1.Zhejiang Univ, Affiliated Hosp 1, Dept Cardiol, Hangzhou, Zhejiang, Peoples R China; 2.Kings Coll London, Sch Cardiovasc Med & Sci, BHF Ctr, 125 Coldharbour Lane, London SE5 9NU, England; 3.Univ Chinese Acad Sci, CAS Ctr Excellence Mol Cell Sci, Chinese Acad Sci,State Key Lab Cell Biol, Shanghai Inst Biol Sci,Inst Biochem & Cell Biol, Shanghai, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Li,Chen, Ting,Xu, Qingbo,et al. Role of Resident Stem Cells in Vessel Formation and Arteriosclerosis[J]. CIRCULATION RESEARCH,2018,122(11):1608-1624. |
APA | Zhang, Li,Chen, Ting,Xu, Qingbo,Bhaloo, Shirin Issa,&Zhou, Bin.(2018).Role of Resident Stem Cells in Vessel Formation and Arteriosclerosis.CIRCULATION RESEARCH,122(11),1608-1624. |
MLA | Zhang, Li,et al."Role of Resident Stem Cells in Vessel Formation and Arteriosclerosis".CIRCULATION RESEARCH 122.11(2018):1608-1624. |
入库方式: OAI收割
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