热门
High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons
文献类型：期刊论文
| 作者 | Sun, Jin1; Wong, Yue Him3; Qian, Pei-Yuan3; Qiu, Jian-Wen1; Chen, Lian Guo3; He, Li Sheng2
|
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2015-11-23 |
| 卷号 | 5 |
| DOI | 10.1038/srep16597 |
| 文献子类 | Article |
| 英文摘要 | Bathymodiolid mussels dominate hydrothermal vents, cold methane/sulfide-hydrocarbon seeps, and other sites of organic enrichment. Here, we aimed to explore the innate immune system and detoxification mechanism of the deep sea mussel Bathymodiolus platifrons collected from a methane seep in the South China Sea. We sequenced the transcriptome of the mussels' gill, foot and mantle tissues and generated a transcriptomic database containing 96,683 transcript sequences. Based on GO and KEGG annotations, we reported transcripts that were related to the innate immune system, heavy metal detoxification and sulfide metabolic genes. Our in-depth analysis on the isoforms of peptidoglycan recognition protein (PGRP) that have different cellular location and potentially differential selectivity towards peptidoglycan (PGN) from gram-positive and gram-negative bacteria were differentially expressed in different tissues. We also reported a potentially novel form of metallothionein and the production of phytochelatin in B. platifrons, which has not been reported in any of its coastal relative Mytilus mussel species. Overall, the present study provided new insights into heavy metal and sulfide metabolism in B. platifrons and can be served as the basis for future molecular studies on host-symbiont interactions in cold seep mussels. |
| WOS关键词 | PEPTIDOGLYCAN RECOGNITION PROTEIN ; HEAVY-METAL DETOXIFICATION ; OUTER-MEMBRANE PROTEIN ; DEEP-SEA MUSSELS ; HYDROTHERMAL VENTS ; TAURINE TRANSPORTER ; METHANE SEEP ; RNA-SEQ ; THIOTROPHIC ENDOSYMBIONTS ; PHYTOCHELATIN SYNTHASE |
| 语种 | 英语 |
| WOS记录号 | WOS:000365085100001 |
| 源URL | [http://124.16.218.2:8080/handle/183446/893]  |
| 专题 | 深海科学研究部_深海生物学研究室_深海生物蛋白质组学及分子生物学研究组 |
| 作者单位 | 1.Hong Kong Baptist Univ, Dept Biol, Hong Kong, Hong Kong, Peoples R China 2.Chinese Acad Sci, Sanya Inst Deep Sea Sci & Engn, Hainan, Peoples R China 3.Hong Kong Univ Sci & Technol, Sch Sci, Div Life Sci, Hong Kong, Hong Kong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Jin,Wong, Yue Him,Qian, Pei-Yuan,et al. High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons[J]. SCIENTIFIC REPORTS,2015,5. |
| APA | Sun, Jin,Wong, Yue Him,Qian, Pei-Yuan,Qiu, Jian-Wen,Chen, Lian Guo,&He, Li Sheng.(2015).High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons.SCIENTIFIC REPORTS,5. |
| MLA | Sun, Jin,et al."High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons".SCIENTIFIC REPORTS 5(2015). |
入库方式： OAI收割
来源：深海科学与工程研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。