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The Enigmatic Genome of an Obligate Ancient Spiroplasma Symbiont in a Hadal Holothurian
文献类型：期刊论文
| 作者 | Danchin, Antoine(Hop La Pitie Salpetriere, Inst Cardiometab & Nutr, Paris, France); Zhu, Fang-Chao2 ; Zhang, Pei-Wei2; He, Li-Sheng2; Huang, Jiao-Mei2; Wang, Yong(Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya, Hainan, Peoples R China); Danchin, Antoine1; Wang, Yong2
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| 刊名 | APPLIED AND ENVIRONMENTAL MICROBIOLOGY
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| 出版日期 | 2018 |
| 卷号 | 84期号:1 |
| 关键词 | Symbiosis Hadal Crispr Genome Reduction Spiroplasma |
| DOI | 10.1128/AEM.01965-17 |
| 产权排序 | 第1完成单位 ; 第2完成单位 |
| 文献子类 | Article |
| 英文摘要 | Protective symbiosis has been reported in many organisms, but the molecular mechanisms of the mutualistic interactions between the symbionts and their hosts are unclear. Here, we sequenced the 424-kbp genome of "Candidatus Spiroplasma holothuricola," which dominated the hindgut microbiome of a sea cucumber, a major scavenger captured in the Mariana Trench (6,140 m depth). Phylogenetic relationships indicated that the dominant bacterium in the hindgut was derived from a basal group of Spiroplasma species. In this organism, the genes responsible for the biosynthesis of amino acids, glycolysis, and sugar transporters were lost, strongly suggesting endosymbiosis. The highly decayed genome consists of two chromosomes and harbors genes coding for proteolysis, microbial toxin, restrictionmethylation systems, and clustered regularly interspaced short palindromic repeats (CRISPRs), composed of three cas genes and 76 CRISPR spacers. The holothurian host is probably protected against invading viruses from sediments by the CRISPRs/Cas and restriction systems of the endosymbiotic spiroplasma. The protective endosymbiosis indicates the important ecological role of the ancient Spiroplasma symbiont in the maintenance of hadal ecosystems. |
| URL标识 | 查看原文 |
| WOS关键词 | PSEUDOMONAS-AERUGINOSA ; MODIFICATION SYSTEMS ; INSECT ENDOSYMBIONT ; GUT MICROBIOTA ; SEQUENCE ; BACTERIA ; METAGENOMES ; WOLBACHIA ; EVOLUTION ; ARGININE |
| 语种 | 英语 |
| WOS记录号 | WOS:000418039700026 |
| 源URL | [http://ir.idsse.ac.cn/handle/183446/5203]  |
| 专题 | 深海科学研究部_深海生物学研究室_深海生物蛋白质组学及分子生物学研究组 深海科学研究部_深海生物学研究室 |
| 通讯作者 | Danchin, Antoine(Hop La Pitie Salpetriere, Inst Cardiometab & Nutr, Paris, France); Wang, Yong(Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya, Hainan, Peoples R China); Danchin, Antoine; Wang, Yong |
| 作者单位 | 1.Hop La Pitie Salpetriere, Inst Cardiometab & Nutr, Paris, France 2.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya, Hainan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Danchin, Antoine,Zhu, Fang-Chao,Zhang, Pei-Wei,et al. The Enigmatic Genome of an Obligate Ancient Spiroplasma Symbiont in a Hadal Holothurian[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY,2018,84(1). |
| APA | Danchin, Antoine.,Zhu, Fang-Chao.,Zhang, Pei-Wei.,He, Li-Sheng.,Huang, Jiao-Mei.,...&Wang, Yong.(2018).The Enigmatic Genome of an Obligate Ancient Spiroplasma Symbiont in a Hadal Holothurian.APPLIED AND ENVIRONMENTAL MICROBIOLOGY,84(1). |
| MLA | Danchin, Antoine,et al."The Enigmatic Genome of an Obligate Ancient Spiroplasma Symbiont in a Hadal Holothurian".APPLIED AND ENVIRONMENTAL MICROBIOLOGY 84.1(2018). |
入库方式： OAI收割
来源：深海科学与工程研究所
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