New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318
文献类型：期刊论文
| 作者 | Yang, Feng-Xian; Hou, Guan-Xiong; Luo, Jianying ; Yang, Jing; Yan, Yijun; Huang, Sheng-Xiong
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| 刊名 | JOURNAL OF ANTIBIOTICS
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| 出版日期 | 2018 |
| 卷号 | 71期号:12页码:1040-1043 |
| ISSN号 | 0021-8820 |
| 英文摘要 | Chemical investigation of a strain Streptomyces sp. KIB-H1318 isolated from soil sample led to the discovery of three new phenoxazinone-related alkaloids 1-3, as well as two known analogs exfoliazone (4) and viridobrunnine A (5). Their structures were determined on the basis of extensive spectroscopic analysis. The antimicrobial activity and cytotoxicity of the isolates were assayed. Exfoliazone and viridobrunnine A exhibited minor antibacterial activity against Escherichia coli ATCC 8099, Bacillus subtilis ATCC 6633, and Staphylococcus aureus ATCC 6538. Compound 2 exhibited low cytotoxicity against two human cancer cell lines HeLa and SW480 with the IC50 values of 36.8 and 37.8 mu M, respectively. |
| 语种 | 英语 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/64674]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Yang, Feng-Xian,Hou, Guan-Xiong,Luo, Jianying,et al. New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318[J]. JOURNAL OF ANTIBIOTICS,2018,71(12):1040-1043. |
| APA | Yang, Feng-Xian,Hou, Guan-Xiong,Luo, Jianying,Yang, Jing,Yan, Yijun,&Huang, Sheng-Xiong.(2018).New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318.JOURNAL OF ANTIBIOTICS,71(12),1040-1043. |
| MLA | Yang, Feng-Xian,et al."New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318".JOURNAL OF ANTIBIOTICS 71.12(2018):1040-1043. |
入库方式： OAI收割
来源：昆明植物研究所
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