中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.

文献类型:期刊论文

作者Yang, Dong-Qiong; Chen, Zhao-Rong; Chen, Duo-Zhi; Hao, Xiao-Jiang; Li, Shun-Lin
刊名Natural products and bioprospecting
出版日期2018
卷号8期号:3页码:189-197
ISSN号2192-2195
英文摘要Fifteen known amaryllidaceae alkaloids were isolated from the bulbs of Lycoris radiata. Some of the compounds and lycoricidine derivatives had been screened for the activities against tobacco mosaic virus (TMV) by the conventional half-leaf method. Lycoricidine derivatives were also carried out the assay of effect on systemic infection of TMV by western-blot and RT-PCR analysis. The tested compounds showed moderate inactivation effect, whereas the lycoricidine derivatives showed good protective effect. The protective inhibitory activity of compounds L1 (N-methyl-2,3,4-trimethoxylycoricidine) (60.8%) and L3 (N-methyl-2-methoxy-3,4-acetonidelycoricidine) (62.0%) was almost similar to the positive control, Ningnanmycin (66.4%). RT-PCR and Western-blot analysis displayed that compounds L1, L3, L5 (N-allyl-2,3,4-triallyloxylycoricidine) exhibited antiviral activity, which was evidenced by reducing TMV-CP gene replication and TMV-CP protein expression. Additionally, defensive enzyme activities confirmed that compound L1 could increase the activity of PAL, POD, SOD to improve disease resistance of tobacco.
语种英语
源URL[http://ir.kib.ac.cn/handle/151853/64810]  
专题中国科学院昆明植物研究所
推荐引用方式
GB/T 7714
Yang, Dong-Qiong,Chen, Zhao-Rong,Chen, Duo-Zhi,et al. Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.[J]. Natural products and bioprospecting,2018,8(3):189-197.
APA Yang, Dong-Qiong,Chen, Zhao-Rong,Chen, Duo-Zhi,Hao, Xiao-Jiang,&Li, Shun-Lin.(2018).Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives..Natural products and bioprospecting,8(3),189-197.
MLA Yang, Dong-Qiong,et al."Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.".Natural products and bioprospecting 8.3(2018):189-197.

入库方式: OAI收割

来源:昆明植物研究所

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