Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18
文献类型：期刊论文
| 作者 | Tang, Jian-Wei1,2,3; Kong, Ling-Mei1,2; Zu, Wen-Yu4; Hu, Kun1,2 ; Li, Xiao-Nian1,2; Yan, Bing-Chao1,2; Wang, Wei-Guang1,2; Sun, Han-Dong1,2; Li, Yan1,2; Puno, Pema-Tenzin1,2
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2019-02-01 |
| 卷号 | 21期号:3页码:771-775 |
| ISSN号 | 1523-7060 |
| 英文摘要 | Isopenicins A-C (1-3), three novel meroterpenoids possessing two types of unprecedented terpenoid-polyketide hybrid skeletons, were isolated from the cultures of Penicillium sp. sh18. Their structures were determined through synergetic use of extensive spectroscopic analysis, quantum-chemical calculation with ANN-PRA analysis, and X-ray crystallographic analysis. Additionally, the inhibitory activities of these compounds on the Wnt/beta-catenin signaling pathway were evaluated, and 1 was identified as a potent inhibitor of the Wnt signaling pathway. |
| 资助项目 | National Natural Science Foundation of China[81874298] ; National Natural Science Foundation of China[81673329] ; National Natural Science Foundation of China[81773783] ; National Natural Science Foundation of China[81603161] |
| 语种 | 英语 |
| 资助机构 | National Natural Science Foundation of China |
| 源URL | [http://ir.kib.ac.cn/handle/151853/64235]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Li, Yan; Puno, Pema-Tenzin |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Yunnan Univ Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tang, Jian-Wei,Kong, Ling-Mei,Zu, Wen-Yu,et al. Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18[J]. ORGANIC LETTERS,2019,21(3):771-775. |
| APA | Tang, Jian-Wei.,Kong, Ling-Mei.,Zu, Wen-Yu.,Hu, Kun.,Li, Xiao-Nian.,...&Puno, Pema-Tenzin.(2019).Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18.ORGANIC LETTERS,21(3),771-775. |
| MLA | Tang, Jian-Wei,et al."Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18".ORGANIC LETTERS 21.3(2019):771-775. |
入库方式： OAI收割
来源：昆明植物研究所
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