New phloroglucinol derivatives with protein tyrosine phosphatase 1B (PTP1B) inhibitory activities from Syzygium austroyunnanense
文献类型：期刊论文
| 作者 | Xu, Shao-Hua1; Xu, Wen1; Wang, Li1,2; Hu, Yi-Kao1; Liu, Jin-Ping1; Zhao, Yan1; Li, Meng-Jia1; Li, Feng1; Huang, Sheng-Xiong2 ; Zhao, Yong1
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| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2018-11-01 |
| 卷号 | 131页码:141-145 |
| ISSN号 | 0367-326X |
| 关键词 | Syzygium austroyunnanense Myrtaceae Phloroglucinol derivatives Structure elucidation PTP 1B inhibitory activities |
| 英文摘要 | Five new phloroglucinol derivatives (1-5) together with one known analogue (6) were isolated from the leaves of Syzygiwn austroyunnanense which is an edible folk medicine used for the treatment of diabetes. The new structures were elucidated as austroyunones A - E (1-5) by means of the extensive spectroscopic analyses including high-resolution electrospray ionization mass spectrometry (HRESIMS) and ID and 2D nuclear magnetic resonance (NMR). Compounds 4-6 showed obvious protein tyrosine phosphatase 1B (PTP1B) inhibitory activity. This discovery of new phloroglucinols and their bioactivities provided a scientific basis for the application of S. austroyunnanense as an edible and medicinal plant. |
| 资助项目 | National Natural Science Foundation of China[31560098] ; Mid-aged and Young Academic and Technical Leader Raising Foundation of Yunnan Province, China[2010CI040] |
| 语种 | 英语 |
| 资助机构 | National Natural Science Foundation of China ; Mid-aged and Young Academic and Technical Leader Raising Foundation of Yunnan Province, China |
| 源URL | [http://ir.kib.ac.cn/handle/151853/64297]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Huang, Sheng-Xiong; Zhao, Yong |
| 作者单位 | 1.Yunnan Normal Univ, Coll Chem & Chem Engn, Kunming 650500, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Shao-Hua,Xu, Wen,Wang, Li,et al. New phloroglucinol derivatives with protein tyrosine phosphatase 1B (PTP1B) inhibitory activities from Syzygium austroyunnanense[J]. FITOTERAPIA,2018,131:141-145. |
| APA | Xu, Shao-Hua.,Xu, Wen.,Wang, Li.,Hu, Yi-Kao.,Liu, Jin-Ping.,...&Zhao, Yong.(2018).New phloroglucinol derivatives with protein tyrosine phosphatase 1B (PTP1B) inhibitory activities from Syzygium austroyunnanense.FITOTERAPIA,131,141-145. |
| MLA | Xu, Shao-Hua,et al."New phloroglucinol derivatives with protein tyrosine phosphatase 1B (PTP1B) inhibitory activities from Syzygium austroyunnanense".FITOTERAPIA 131(2018):141-145. |
入库方式： OAI收割
来源：昆明植物研究所
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