Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans
文献类型：期刊论文
| 作者 | Wang, Wen-Xuan1; Lei, Xinxiang1; Ai, Hong-Lian1; Bai, Xue2; Li, Jing1 ; He, Juan1; Li, Zheng-Hui1; Zheng, Yong-Sheng1; Feng, Tao1; Liu, Ji-Kai1
|
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2019-02-15 |
| 卷号 | 21期号:4页码:1108-1111 |
| ISSN号 | 1523-7060 |
| 英文摘要 | Curtachalasins C-E (1-3), which have an unprecedent bridged 6/6/6/6 ring system, were identified from the endophytic fungus Xylaria cf. curta. Residual dipolar coupling analyses associating with density functional theory calculations were utilized to determine the relative configuration of noncrystallizable compound 2. The absolute configurations of 1-3 were determined by X-ray diffraction and electronic circular dichroism calculations. Remarkably, curtachalasin C (1) showed significant resistance reversal activity against fluconazole-resistant Candida albicans. |
| 资助项目 | National Natural Science Foundation of China[31801789] ; National Natural Science Foundation of China[31560010] ; National Natural Science Foundation of China[31870513] ; National Natural Science Foundation of China[81872762] ; National Natural Science Foundation of China[81773590] ; National Natural Science Foundation of China[81561148013] ; National Natural Science Foundation of China[21502239] ; National Natural Science Foundation of China[81803395] ; National Key RD Plan[2017YFC1704007] ; South-Central University for Nationalities |
| 语种 | 英语 |
| 资助机构 | National Natural Science Foundation of China ; National Key RD Plan ; South-Central University for Nationalities |
| 源URL | [http://ir.kib.ac.cn/handle/151853/64598]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Ai, Hong-Lian; Feng, Tao; Liu, Ji-Kai |
| 作者单位 | 1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Wen-Xuan,Lei, Xinxiang,Ai, Hong-Lian,et al. Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans[J]. ORGANIC LETTERS,2019,21(4):1108-1111. |
| APA | Wang, Wen-Xuan.,Lei, Xinxiang.,Ai, Hong-Lian.,Bai, Xue.,Li, Jing.,...&Liu, Ji-Kai.(2019).Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans.ORGANIC LETTERS,21(4),1108-1111. |
| MLA | Wang, Wen-Xuan,et al."Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans".ORGANIC LETTERS 21.4(2019):1108-1111. |
入库方式： OAI收割
来源：昆明植物研究所
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