Norascyronones A and B, 2,3,4-nor-Polycyclic Polyprenylated Acylphloroglucinols from Hypericum ascyron
文献类型：期刊论文
| 作者 | Hu, Ya-Li1,2,3; Hu, Kun1,2 ; Kong, Ling-Mei1,2,3; Xia, Fan1,2,3; Yang, Xing-Wei1,2; Xu, Gang1,2
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2019-02-15 |
| 卷号 | 21期号:4页码:1007-1010 |
| ISSN号 | 1523-7060 |
| 英文摘要 | Phytochemical study of Hypericum ascyron led to the characterization of norascyronones A-C (1-3), metabolites derived from bicyclic polyprenylated acylphloroglucinols by losing eight carbons (C-2/3/4 of core and the isoprenyl at C-3). Compounds 1/2 with an unprecedented 6/6/5/6 ring system should be generated via [4 + 2] intramolecular cyclization of 3. Their structures were determined by spectroscopic and X-ray diffraction data. Compounds 1 and 2 showed cytotoxicities against the SK-BR-3 cell line (IC50 4.3 and 7.8 mu M). |
| 资助项目 | National Natural Sciences Foundation of China[31800296] ; Natural Sciences Foundation of Yunnan Province[2016FB017] ; Kunming Institute of Botany[KIB2017001] ; Southeast Asia Biodiversity Research Institute[2017CASSEABRIQG003] ; CAS, Yunnan Key Laboratory of Natural Medicinal Chemistry[52017-ZZ11] ; Youth Innovation Promotion Association CAS[2016350] |
| 语种 | 英语 |
| 资助机构 | National Natural Sciences Foundation of China ; Natural Sciences Foundation of Yunnan Province ; Kunming Institute of Botany ; Southeast Asia Biodiversity Research Institute ; CAS, Yunnan Key Laboratory of Natural Medicinal Chemistry ; Youth Innovation Promotion Association CAS |
| 源URL | [http://ir.kib.ac.cn/handle/151853/64640]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Yang, Xing-Wei; Xu, Gang |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Ya-Li,Hu, Kun,Kong, Ling-Mei,et al. Norascyronones A and B, 2,3,4-nor-Polycyclic Polyprenylated Acylphloroglucinols from Hypericum ascyron[J]. ORGANIC LETTERS,2019,21(4):1007-1010. |
| APA | Hu, Ya-Li,Hu, Kun,Kong, Ling-Mei,Xia, Fan,Yang, Xing-Wei,&Xu, Gang.(2019).Norascyronones A and B, 2,3,4-nor-Polycyclic Polyprenylated Acylphloroglucinols from Hypericum ascyron.ORGANIC LETTERS,21(4),1007-1010. |
| MLA | Hu, Ya-Li,et al."Norascyronones A and B, 2,3,4-nor-Polycyclic Polyprenylated Acylphloroglucinols from Hypericum ascyron".ORGANIC LETTERS 21.4(2019):1007-1010. |
入库方式： OAI收割
来源：昆明植物研究所
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