Lycodine-Type Lycopodium Alkaloids from the Whole Plants of Huperzia serrata.
文献类型：期刊论文
| 作者 | Liu, Yu-Chen; Zhang, Zhi-Jun; Su, Jia; Peng, Li-Yan; Pan, Lu-Tai; Wu, Xing-De; Zhao, Qin-Shi
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| 刊名 | Natural products and bioprospecting
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:5页码:405-411 |
| ISSN号 | 2192-2195 |
| 英文摘要 | Three new lycodine-type Lycopodium alkaloids, namely 1-methyllycodine (1), 8alpha-hydroxy-15,16-dehydro-des-N-methyl-alpha-obscurine (2), N-methyl-16-hydroxyhuperzine B (3), and one new natural lycodine-type Lycopodium alkaloid, N-methylhuperzine A (4), along with 11 known analogues (5-15), were isolated from the whole plants of club moss Huperzia serrata. The structures of 1-4 were elucidated on the basis of NMR spectroscopic and mass spectrometry data. Among them, compound 1 was the first lycodine-type alkaloid possessing a methyl group at C-1. In addition, the structure of 5 was confirmed by the single-crystal X-ray crystallography data and its 13C NMR was reported for the first time in current study. Compounds 1-5 were tested their BACE1 inhibitory activity. |
| 源URL | [http://ir.kib.ac.cn/handle/151853/64830]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu, Yu-Chen,Zhang, Zhi-Jun,Su, Jia,et al. Lycodine-Type Lycopodium Alkaloids from the Whole Plants of Huperzia serrata.[J]. Natural products and bioprospecting,2017,7(5):405-411. |
| APA | Liu, Yu-Chen.,Zhang, Zhi-Jun.,Su, Jia.,Peng, Li-Yan.,Pan, Lu-Tai.,...&Zhao, Qin-Shi.(2017).Lycodine-Type Lycopodium Alkaloids from the Whole Plants of Huperzia serrata..Natural products and bioprospecting,7(5),405-411. |
| MLA | Liu, Yu-Chen,et al."Lycodine-Type Lycopodium Alkaloids from the Whole Plants of Huperzia serrata.".Natural products and bioprospecting 7.5(2017):405-411. |
入库方式： OAI收割
来源：昆明植物研究所
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