Clerodane Diterpenoids with Anti-hyperglycemic Activity from Tinospora crispa.
文献类型：期刊论文
| 作者 | Gao, Yuan; Niu, Yan-Fen; Wang, Fei; Hai, Ping; Wang, Fang; Fang, Yin-Dong; Xiong, Wen-Yong ; Liu, Ji-Kai
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| 刊名 | Natural products and bioprospecting
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| 出版日期 | 2016 |
| 卷号 | 6期号:5页码:247-255 |
| ISSN号 | 2192-2195 |
| 英文摘要 | Four new clerodane diterpenoids, tinosporols A-C (2-4) and tinosporoside A (5), together with six known analogues were isolated from the vines of Tinospora crispa. Their structures were established by extensive spectroscopic analysis. The relative configuration at C-12 in the known diterpenoid borapetoside E (1), the major component of the plant, was firstly established with the aid of molecular model. Compound 1 significantly reduced serum glucose levels at dose-dependent manners in alloxan-induced hyperglycemic mice and db/db type 2 diabetic mice. |
| 源URL | [http://ir.kib.ac.cn/handle/151853/64870]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Gao, Yuan,Niu, Yan-Fen,Wang, Fei,et al. Clerodane Diterpenoids with Anti-hyperglycemic Activity from Tinospora crispa.[J]. Natural products and bioprospecting,2016,6(5):247-255. |
| APA | Gao, Yuan.,Niu, Yan-Fen.,Wang, Fei.,Hai, Ping.,Wang, Fang.,...&Liu, Ji-Kai.(2016).Clerodane Diterpenoids with Anti-hyperglycemic Activity from Tinospora crispa..Natural products and bioprospecting,6(5),247-255. |
| MLA | Gao, Yuan,et al."Clerodane Diterpenoids with Anti-hyperglycemic Activity from Tinospora crispa.".Natural products and bioprospecting 6.5(2016):247-255. |
入库方式： OAI收割
来源：昆明植物研究所
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