Effects of Traditional Chinese Medicinal Plants on Anti-insulin Resistance Bioactivity of DXMS-Induced Insulin Resistant HepG2 Cells.
文献类型：期刊论文
| 作者 | Ma, Jun-Zeng; Yang, Li-Xin; Shen, Xiao-Ling; Qin, Ji-Huan; Deng, Li-Lan; Ahmed, Selena; Xu, Hong-Xi; Xue, Da-Yuan; Ye, Jiang-Xia; Xu, Gang
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| 刊名 | Natural products and bioprospecting
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| 出版日期 | 2014 |
| 卷号 | 4期号:4页码:197-206 |
| ISSN号 | 2192-2195 |
| 英文摘要 | ABSTRACT: Medicinal plants have a long history of use in China to treat diabetic symptoms. Ancient Chinese medical manuscripts and ethnobotanical surveys document plant remedies that continue to be actively used in China for the treatment of diabetic symptoms. Based on a systematic ancient Chinese medical manuscripts review in combination with ethnobotanical survey, 16 medicinal plants for the traditional treatment of diabetic symptoms were identified for the evaluation of anti-insulin resistance bioactivity. The biological activity of 16 medicinal plants was tested on dexamethasone (DXMS)-induced insulin resistant HepG2 cells. The result shows that 11 of the 16 medicinal plants enhanced glucose uptake of DXMS-induced insulin resistant HepG2 cells, thereby demonstrating their ability to increase insulin sensitivity, other five medicinal plants including Astragalus membranaceus were found ineffective. The study shows that ancient Chinese medical manuscripts and ethnobotanical surveys on plants for the prevention and treatment of diabetic symptoms provide a promising knowledge base for drug discovery to mitigate the global diabetes epidemic. |
| 源URL | [http://ir.kib.ac.cn/handle/151853/64911]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Ma, Jun-Zeng,Yang, Li-Xin,Shen, Xiao-Ling,et al. Effects of Traditional Chinese Medicinal Plants on Anti-insulin Resistance Bioactivity of DXMS-Induced Insulin Resistant HepG2 Cells.[J]. Natural products and bioprospecting,2014,4(4):197-206. |
| APA | Ma, Jun-Zeng.,Yang, Li-Xin.,Shen, Xiao-Ling.,Qin, Ji-Huan.,Deng, Li-Lan.,...&Xu, Gang.(2014).Effects of Traditional Chinese Medicinal Plants on Anti-insulin Resistance Bioactivity of DXMS-Induced Insulin Resistant HepG2 Cells..Natural products and bioprospecting,4(4),197-206. |
| MLA | Ma, Jun-Zeng,et al."Effects of Traditional Chinese Medicinal Plants on Anti-insulin Resistance Bioactivity of DXMS-Induced Insulin Resistant HepG2 Cells.".Natural products and bioprospecting 4.4(2014):197-206. |
入库方式： OAI收割
来源：昆明植物研究所
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