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Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris

文献类型：期刊论文

作者Tian Minqing1,3; Dai Haofu2; Li Xiaoming1; Wang Bingui1
刊名CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
出版日期2009-06-01
卷号27期号:2页码:288-296
关键词Mangrove Sonneratia Caseolaris Chemical Constituents Cytotoxic Assay
ISSN号0254-4059
DOI10.1007/s00343-009-9138-7
文献子类Article
英文摘要Twenty-four compounds including eight steroids (1-8), nine triterpenoids (9-16, 24), three flavonoids (20-22), and four benzenecarboxylic derivatives (17-19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4-20 and 22-24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3',4',5,7-tetrahydroxyflavone) exhibited significant activity with IC(50) 2.8 mu g/mL, while oleanolic acid (14), 3,3'-di-O-methyl ether ellagic acid (18), and 3,3',4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites.; Twenty-four compounds including eight steroids (1-8), nine triterpenoids (9-16, 24), three flavonoids (20-22), and four benzenecarboxylic derivatives (17-19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4-20 and 22-24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3',4',5,7-tetrahydroxyflavone) exhibited significant activity with IC50 2.8 mu g/mL, while oleanolic acid (14), 3,3'-di-O-methyl ether ellagic acid (18), and 3,3',4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites.
学科主题Limnology ; Oceanography
URL标识查看原文
语种英语
WOS记录号WOS:000267970300013
公开日期2010-12-22
源URL[http://ir.qdio.ac.cn/handle/337002/3023]  
专题海洋研究所_实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, State Key Lab Trop Crops Biotechnol, Haikou 571101, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714		 Tian Minqing,Dai Haofu,Li Xiaoming,et al. Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2009,27(2):288-296.
APA Tian Minqing,Dai Haofu,Li Xiaoming,&Wang Bingui.(2009).Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,27(2),288-296.
MLA Tian Minqing,et al."Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 27.2(2009):288-296.

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来源：海洋研究所

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