Comparison of two marine sponge-associated Penicillium strains DQ25 and SC10: differences in secondary metabolites and their bioactivities
文献类型：期刊论文
| 作者 | Wei, Rongbian1,2; Li, Fuchao3; Song, Ru4; Qin, Song3 |
| 刊名 | ANNALS OF MICROBIOLOGY
 |
| 出版日期 | 2009 |
| 卷号 | 59期号:3页码:579-585 |
| 关键词 | Symbiotic Fungi Marine Sponge Secondary Metabolites Biological Activity |
| ISSN号 | 1590-4261 |
| 文献子类 | Article |
| 英文摘要 | Two strains of Penicillium, DQ25 and SC10, isolated from marine sponge Haliclona angulata (Bowerbank) and Hymeniacidon sp. respectively, were subjected to stationary cultivation under GYP medium for 30 days. The fermentation extracts were undergone bioactivities assays against human pathogens, phytopathogenic fungi and brine shrimp (Artemia salina). Bioassays-guided compounds isolation was performed by Silica gel columns and Sephadex LH-20 chromatography. Spectroscopic methods were used to structures elucidation of the compounds. Results showed the activities of secondary metabolites of strain DQ25 were generally stronger than that of strain SC10. Major bioactive molecules isolated from strain DQ25 were a 1,4-naphthoquinone derivative and an unidentified alkaloid. The two components were not isolated from the extract of strain SC10. ITS sequences revealed that these two species have the greatest similarity with Penicillium vinaceum and Penicillium granulatum respectively.; Two strains of Penicillium, DQ25 and SC10, isolated from marine sponge Haliclona angulata (Bowerbank) and Hymeniacidon sp. respectively, were subjected to stationary cultivation under GYP medium for 30 days. The fermentation extracts were undergone bioactivities assays against human pathogens, phytopathogenic fungi and brine shrimp (Artemia salina). Bioassays-guided compounds isolation was performed by Silica gel columns and Sephadex LH-20 chromatography. Spectroscopic methods were used to structures elucidation of the compounds. Results showed the activities of secondary metabolites of strain DQ25 were generally stronger than that of strain SC10. Major bioactive molecules isolated from strain DQ25 were a 1,4-naphthoquinone derivative and an unidentified alkaloid. The two components were not isolated from the extract of strain SC10. ITS sequences revealed that these two species have the greatest similarity with Penicillium vinaceum and Penicillium granulatum respectively. |
| 学科主题 | Biotechnology & Applied Microbiology ; Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000271346700028 |
| 公开日期 | 2010-12-22 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/3039]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.China Pharmaceut Univ, Sch Life Sci & Technol, Nanjing 210018, Peoples R China 2.Zhejiang Ocean Univ, Coll Marine Sci, Zhoushan 316004, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Open Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 4.Ocean Univ China, Coll Food Sci, Qingdao 266003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wei, Rongbian,Li, Fuchao,Song, Ru,et al. Comparison of two marine sponge-associated Penicillium strains DQ25 and SC10: differences in secondary metabolites and their bioactivities[J]. ANNALS OF MICROBIOLOGY,2009,59(3):579-585. |
| APA | Wei, Rongbian,Li, Fuchao,Song, Ru,&Qin, Song.(2009).Comparison of two marine sponge-associated Penicillium strains DQ25 and SC10: differences in secondary metabolites and their bioactivities.ANNALS OF MICROBIOLOGY,59(3),579-585. |
| MLA | Wei, Rongbian,et al."Comparison of two marine sponge-associated Penicillium strains DQ25 and SC10: differences in secondary metabolites and their bioactivities".ANNALS OF MICROBIOLOGY 59.3(2009):579-585. |
入库方式： OAI收割
来源：海洋研究所
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