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Natural bromophenols from the marine red alga Polysiphonia urceolata (Rhodomelaceae): Structural elucidation and DPPH radical-scavenging activity

文献类型：期刊论文

作者Li, Ke; Li, Xiao-Ming; Ji, Nai-Yun; Wang, Bin-Gui
刊名BIOORGANIC & MEDICINAL CHEMISTRY
出版日期2007-11-01
卷号15期号:21页码:6627-6631
关键词Dpph Radical-scavenging Activity Marine Red Alga Polysiphonia Urceolata Bromophenols
ISSN号0968-0896
DOI10.1016/j.bmc.2007.08.023
文献子类Article
英文摘要Three new natural occurring bromophenols, 3-(3-bromo-4,5-dihydroxyphenyl)-2-(3,5-dibromo-4-hydroxyphenyl)propionic acid (1), (E)-4-(3-bromo-4,5-dihydroxyphenyl)-but-3-en-2-one (2), and (3,5-dibromo-4-hydroxyphenyl) acetic acid butyl ester (3), together with one known bromophenol, 1,2-bis(3-bromo-4,5-dihydroxyphenyl)ethane (4), were isolated and identified from the marine red alga Polysiphonia urceolata. The structures of these compounds were elucidated by extensive analysis of ID and 2D NMR and IR spectra and MS data. Each of the isolated compounds was evaluated for scavenging alpha,alpha-diphenyl-beta-picrylhydrazyl (DPPH) radical activity and all of them exhibited significant activity with IC50 values ranging from 9.67 to 21.90 mu M, compared to the positive control, a well-known antioxidant butylated hydroxytoluene (BHT), with IC50 83.84 mu M. (C) 2007 Elsevier Ltd. All rights reserved.; Three new natural occurring bromophenols, 3-(3-bromo-4,5-dihydroxyphenyl)-2-(3,5-dibromo-4-hydroxyphenyl)propionic acid (1), (E)-4-(3-bromo-4,5-dihydroxyphenyl)-but-3-en-2-one (2), and (3,5-dibromo-4-hydroxyphenyl) acetic acid butyl ester (3), together with one known bromophenol, 1,2-bis(3-bromo-4,5-dihydroxyphenyl)ethane (4), were isolated and identified from the marine red alga Polysiphonia urceolata. The structures of these compounds were elucidated by extensive analysis of ID and 2D NMR and IR spectra and MS data. Each of the isolated compounds was evaluated for scavenging alpha,alpha-diphenyl-beta-picrylhydrazyl (DPPH) radical activity and all of them exhibited significant activity with IC50 values ranging from 9.67 to 21.90 mu M, compared to the positive control, a well-known antioxidant butylated hydroxytoluene (BHT), with IC50 83.84 mu M. (C) 2007 Elsevier Ltd. All rights reserved.
学科主题Biochemistry & Molecular Biology ; Chemistry, Medicinal ; Chemistry, Organic
URL标识查看原文
语种英语
WOS记录号WOS:000250179600001
公开日期2010-12-24
源URL[http://ir.qdio.ac.cn/handle/337002/5595]  
专题海洋研究所_实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,et al. Natural bromophenols from the marine red alga Polysiphonia urceolata (Rhodomelaceae): Structural elucidation and DPPH radical-scavenging activity[J]. BIOORGANIC & MEDICINAL CHEMISTRY,2007,15(21):6627-6631.
APA Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,&Wang, Bin-Gui.(2007).Natural bromophenols from the marine red alga Polysiphonia urceolata (Rhodomelaceae): Structural elucidation and DPPH radical-scavenging activity.BIOORGANIC & MEDICINAL CHEMISTRY,15(21),6627-6631.
MLA Li, Ke,et al."Natural bromophenols from the marine red alga Polysiphonia urceolata (Rhodomelaceae): Structural elucidation and DPPH radical-scavenging activity".BIOORGANIC & MEDICINAL CHEMISTRY 15.21(2007):6627-6631.

入库方式： OAI收割

来源：海洋研究所

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