Transcriptome, antioxidant enzyme activity and histopathology analysis of hepatopancreas from the white shrimp Litopenaeus vannamei fed with aflatoxin 131(AFB1)
文献类型：期刊论文
| 作者 | Zhao, Wei1,3; Wang, Lei1,2; Liu, Mei1,2; Jiang, Keyong1,2; Wang, Mengqiang1,2 ; Yang, Guang3; Qi, Cancan1,2; Wang, Baojie1,2
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| 刊名 | DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
 |
| 出版日期 | 2017-09-01 |
| 卷号 | 74页码:69-81 |
| 关键词 | Litopenaeus Vannamei Hepatopancreas Aflatoxin B1 Transcriptome Enzyme Activity Histopathology |
| DOI | 10.1016/j.dci.2017.03.031 |
| 文献子类 | Article |
| 英文摘要 | Aflatoxin produced by Aspergillus flavus or Aspergillus parasiticus fungi during grain and feed processing and storage. Aflatoxins cause severe health problems reducing the yield and profitability of shrimp cultures. We sought to understand the interaction between shrimp immunity and aflatoxin B1 (AFB1), analyzing transcriptome expression, antioxidant enzyme activity, and histological features of the hepatopancreas of shrimp fed with AFB1. From over 4 million high-quality reads, de novo unigene assembly produced 103,644 fully annotated genes. A total of 1024 genes were differentially expressed in shrimp fed with AFB1, being involved in functions, such as peroxidase metabolism, signal transduction, transcriptional control, apoptosis, proteolysis, endocytosis, and cell adhesion and cell junction. Upon AFB1 challenge, there were severe histological alterations in shrimp hepatopancreas. AFB1 challenge increased the activity of several antioxidant enzymes. Our data contribute to improve the current understanding of host-AFB1 interaction, providing an abundant source for identification of novel genes. (C) 2017 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000403512600009 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/137148]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China 3.Tianjin Agr Univ, Coll Fishery Sci, Tianjin Key Lab Aquaculture, Tianjin 300384, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Wei,Wang, Lei,Liu, Mei,et al. Transcriptome, antioxidant enzyme activity and histopathology analysis of hepatopancreas from the white shrimp Litopenaeus vannamei fed with aflatoxin 131(AFB1)[J]. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,2017,74:69-81. |
| APA | Zhao, Wei.,Wang, Lei.,Liu, Mei.,Jiang, Keyong.,Wang, Mengqiang.,...&Wang, Baojie.(2017).Transcriptome, antioxidant enzyme activity and histopathology analysis of hepatopancreas from the white shrimp Litopenaeus vannamei fed with aflatoxin 131(AFB1).DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,74,69-81. |
| MLA | Zhao, Wei,et al."Transcriptome, antioxidant enzyme activity and histopathology analysis of hepatopancreas from the white shrimp Litopenaeus vannamei fed with aflatoxin 131(AFB1)".DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 74(2017):69-81. |
入库方式： OAI收割
来源：海洋研究所
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