Polysaccharides from Sargassum thunbergii: Monthly variations and anti-complement and anti-tumour activities
文献类型：期刊论文
| 作者 | Jin, Weihua1,2; Liu, Ge2,3; Zhong, Weihong1; Sun, Chaomin2,4; Zhang, Quanbin2,4 |
| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
 |
| 出版日期 | 2017-12-01 |
| 卷号 | 105页码:1526-1531 |
| 关键词 | Sargassum Thunbergii Anti-complement Activities Anti-tumour Activities |
| DOI | 10.1016/j.ijbiomac.2017.05.104 |
| 文献子类 | Article |
| 英文摘要 | Monthly variations of polysaccharides from Sargassum thunbergii and their anti-complement and anti-tumour activities were investigated. It was observed that an increase in fucose and total sugar contents occurred during the growth period (from early April to mid-June), accompanied by a decrease in molar ratios of other monosaccharides to fucose. The highest yields were obtained from early July to early September, which was in accordance with the significant increase in, molar ratio of glucose to fucose and decrease in molar ratio of other monosaccharides to fucose. And the above results suggested that S. Thunbergii synthesized large amount of laminaran, the storage substance of brown algae, during the senescence period. However, sulfate contents were relatively stable in the life cycle of S. thunbergii. These results suggested that S. thunbergii synthesized complex sulfated heteropolysacchairdes during inactive period, while during other periods, it synthesized more sulfated galactofucan. All polysaccharides showed anti-complement activity, suggesting that the harvesting time did not influence the anti-complement activities. In the anti-tumour assay in vitro, the polysaccharides taken during the senescence period had much lower anti-tumour activity, suggesting that fucoidan, but not laminaran, determined the anti-tumour activities. Therefore, polysaccharides from S. thunbergii might have great potential in anti-complement and anti-tumour application. (C) 2017 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000415779800021 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/143064]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Zhejiang Univ Technol, Coll Biotechnol & Bioengn, Hangzhou 310014, Zhejiang, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Lab Expt Marine Biol, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin, Weihua,Liu, Ge,Zhong, Weihong,et al. Polysaccharides from Sargassum thunbergii: Monthly variations and anti-complement and anti-tumour activities[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2017,105:1526-1531. |
| APA | Jin, Weihua,Liu, Ge,Zhong, Weihong,Sun, Chaomin,&Zhang, Quanbin.(2017).Polysaccharides from Sargassum thunbergii: Monthly variations and anti-complement and anti-tumour activities.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,105,1526-1531. |
| MLA | Jin, Weihua,et al."Polysaccharides from Sargassum thunbergii: Monthly variations and anti-complement and anti-tumour activities".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 105(2017):1526-1531. |
入库方式： OAI收割
来源：海洋研究所
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