Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas
文献类型：期刊论文
| 作者 | Song, Kai1,2,3; Li, Yingxiang1,2,4 ; Huang, Baoyu1,2,4; Li, Li1,2,3; Zhang, Guofan1,2,4
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| 刊名 | DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
 |
| 出版日期 | 2017-12-01 |
| 卷号 | 77页码:17-22 |
| 关键词 | Evolution Pattern Innate Immune Gene Nucleotide Diversity Crassostrea Gigas Oyster |
| DOI | 10.1016/j.dci.2017.07.012 |
| 文献子类 | Article |
| 英文摘要 | The invertebrate innate immune system functions in immune defence and the stress response. However, knowledge of the genetic and evolutionary patterns of innate immune genes in Mollusca is limited, especially for oysters. Such information would help clarify how oysters adapt to pathogen-rich environments. Here, we characterized the genetic and evolutionary patterns of the innate immune genes in Crassostrea gigas, using population diversity analysis and evolution rates comparison. Innate immune genes have higher median nucleotide diversity than non-immune genes. Nucleotide diversity varied with functional regions and different immune-related gene families. Evolutionary analysis of two Crassostrea species showed that the innate immune genes are less conserved and have higher rates of evolution in C gigas. We also noted a positive association between nucleotide diversity and selective pressures for genes having orthologues. Our findings will help determine the evolutionary patterns of innate immune genes and the association of these genes with mollusc immunity. (C) 2017 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000413387100002 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/143232]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 海洋研究所_海洋生物技术研发中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China 2.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Shandong, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries & Aquaculture, Qingdao 266071, Shandong, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Kai,Li, Yingxiang,Huang, Baoyu,et al. Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas[J]. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,2017,77:17-22. |
| APA | Song, Kai,Li, Yingxiang,Huang, Baoyu,Li, Li,&Zhang, Guofan.(2017).Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas.DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,77,17-22. |
| MLA | Song, Kai,et al."Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas".DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 77(2017):17-22. |
入库方式： OAI收割
来源：海洋研究所
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