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Preparation, structural characterization and in vitro antitumor activity of kappa-carrageenan oligosaccharide fraction from Kappaphycus striatum

文献类型：期刊论文

作者Yuan, HM; Song, JM
刊名JOURNAL OF APPLIED PHYCOLOGY
出版日期2005
卷号17期号:1页码:7-13
关键词Kappa-carrageenan Kappaphycus Striatum Oligosaccharides Antitumor
ISSN号0921-8971
DOI10.1007/s10811-005-5513-8
文献子类Article
英文摘要Oligosaccharides were prepared through mild hydrochloric acid hydrolysis of kappa-carrageenan from Kappaphycus striatum to compare the antitumor activity with carrageenan polysaccharides. Oligosaccharide fractions were isolated by gel permeation chromatography and the structure of fraction 1 (F1) was studied by using negative- ion electrospray ionization-mass spectrometry (ESI-MS), and H-1 and C-13-NMR spectrometry. The in vitro antitumor effects in three human neoplastic cell lines (KB, BGC, and Hela) of polysaccharides and F1 were investigated. The bioassay results showed that F1 exhibited relatively higher antitumor activity against the three cancer cells than polysaccharides.; Oligosaccharides were prepared through mild hydrochloric acid hydrolysis of kappa-carrageenan from Kappaphycus striatum to compare the antitumor activity with carrageenan polysaccharides. Oligosaccharide fractions were isolated by gel permeation chromatography and the structure of fraction 1 (F1) was studied by using negative- ion electrospray ionization-mass spectrometry (ESI-MS), and H-1 and C-13-NMR spectrometry. The in vitro antitumor effects in three human neoplastic cell lines (KB, BGC, and Hela) of polysaccharides and F1 were investigated. The bioassay results showed that F1 exhibited relatively higher antitumor activity against the three cancer cells than polysaccharides.
学科主题Biotechnology & Applied Microbiology ; Marine & Freshwater Biology
URL标识查看原文
语种英语
WOS记录号WOS:000229904700002
公开日期2010-12-22
源URL[http://ir.qdio.ac.cn/handle/337002/2707]  
专题海洋研究所_海洋生态与环境科学重点实验室
海洋研究所_海洋地质与环境重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714		 Yuan, HM,Song, JM. Preparation, structural characterization and in vitro antitumor activity of kappa-carrageenan oligosaccharide fraction from Kappaphycus striatum[J]. JOURNAL OF APPLIED PHYCOLOGY,2005,17(1):7-13.
APA Yuan, HM,&Song, JM.(2005).Preparation, structural characterization and in vitro antitumor activity of kappa-carrageenan oligosaccharide fraction from Kappaphycus striatum.JOURNAL OF APPLIED PHYCOLOGY,17(1),7-13.
MLA Yuan, HM,et al."Preparation, structural characterization and in vitro antitumor activity of kappa-carrageenan oligosaccharide fraction from Kappaphycus striatum".JOURNAL OF APPLIED PHYCOLOGY 17.1(2005):7-13.

入库方式： OAI收割

来源：海洋研究所

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