Visualizing chemical interactions in life sciences with wide-field fluorescence microscopy towards the single-molecule level
文献类型：期刊论文
| 作者 | Gai, Hongwei2; Stayton, Isaac1; Liu, Xin3; Lin, Bingcheng3; Ma, Yinfa1 |
| 刊名 | trac-trends in analytical chemistry
 |
| 出版日期 | 2007-11-01 |
| 卷号 | 26期号:10页码:980-992 |
| 关键词 | fluorescence interaction single-molecule imaging wide-field microscopy |
| 产权排序 | 3;1 |
| 通讯作者 | yinfa ma |
| 英文摘要 | systematic understanding of dynamic biological networks is grounded at the molecular level. knowledge at this level will discover the functions of molecular components and their interactions with cells or among the molecules themselves. single-molecule detection has proved to be an indispensable technique for characterizing molecular interactions in various physiological conditions. among the single-molecule-detection methods, wide-field microscopy-based fluorescence imaging is unique in that dynamic single-molecule events can be vividly observed in a wide observation field. such a technique has obvious advantages for direct tracking of the pathways and processes of molecular interactions and giving visual information about the molecular mechanisms of many biological events. we discuss experimental schemes and applications of wide-field fluorescence microscopy in characterizing biological molecular interactions and studying virus-cell or particle-cell interactions. (c) 2007 elsevier ltd. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | internal-reflection fluorescence ; capillary-zone-electrophoresis ; resonance energy-transfer ; real-time ; living cells ; protein interactions ; rna-polymerase ; dna-molecules ; radial migration ; planar zone |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000251696700010 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/99499]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Univ Missouri, Dept Chem, Rolla, MO 65409 USA 2.Hunan Univ, Ctr Biomed Engn, Changsha 410082, Hunan, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 160023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gai, Hongwei,Stayton, Isaac,Liu, Xin,et al. Visualizing chemical interactions in life sciences with wide-field fluorescence microscopy towards the single-molecule level[J]. trac-trends in analytical chemistry,2007,26(10):980-992. |
| APA | Gai, Hongwei,Stayton, Isaac,Liu, Xin,Lin, Bingcheng,&Ma, Yinfa.(2007).Visualizing chemical interactions in life sciences with wide-field fluorescence microscopy towards the single-molecule level.trac-trends in analytical chemistry,26(10),980-992. |
| MLA | Gai, Hongwei,et al."Visualizing chemical interactions in life sciences with wide-field fluorescence microscopy towards the single-molecule level".trac-trends in analytical chemistry 26.10(2007):980-992. |
入库方式： OAI收割
来源：大连化学物理研究所
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