Preparation of low-molecular-weight and high-sulfate-content chitosans under microwave radiation and their potential antioxidant activity in vitro
文献类型：期刊论文
| 作者 | Xing, RE ; Liu, S; Yu, HH; Zhang, QB; Li, Z; Li, PC
|
| 刊名 | CARBOHYDRATE RESEARCH
 |
| 出版日期 | 2004-10-20 |
| 卷号 | 339期号:15页码:2515-2519 |
| 关键词 | Microwave Radiation Chitosans Traditional Heating Low-molecular-weight And High-sulfate-content Antioxidant Activity Superoxide Radical Hydroxyl Radical |
| ISSN号 | 0008-6215 |
| DOI | 10.1016/j.carres.2004.08.013 |
| 文献子类 | Article |
| 英文摘要 | In the present paper microwave radiation has been used to introduce N-sulfo and O-sulfo groups into chitosan with a thigh degree of substitution and low-molecular weight. The sulfation of chitosan was performed in microwave ovens. It was found that microwave heating is a convenient way to obtain a wide range of products of different degrees of substitution and molecular weight only by changing reaction time or/and radiation power. Moreover, microwave radiation accelerated the degradation of sulfated chitosan, and the molecular weight of sulfated chitosan was considerably lower than that obtained by traditional heating. There are no differences in the chemical structure of sulfated chitosan obtained by microwave and by conventional technology. FTIR and (13)C NMR spectral analyses demonstrated that a significantly shorter time is required to obtain a satisfactory degree of substitution and molecular weight by microwave radiation than by conventional technology. In this present paper, we also determined antioxidant activity of low-molecular-weight and high-sulfate-content chitosans (LCTS). The results showed LCTS could scavenge superoxide and hydroxyl radical. Its IC(50) is 0.025 and 1.32mg/mL, respectively. It is a potential antioxidant in vitro. (C) 2004 Published by Elsevier Ltd.; In the present paper microwave radiation has been used to introduce N-sulfo and O-sulfo groups into chitosan with a thigh degree of substitution and low-molecular weight. The sulfation of chitosan was performed in microwave ovens. It was found that microwave heating is a convenient way to obtain a wide range of products of different degrees of substitution and molecular weight only by changing reaction time or/and radiation power. Moreover, microwave radiation accelerated the degradation of sulfated chitosan, and the molecular weight of sulfated chitosan was considerably lower than that obtained by traditional heating. There are no differences in the chemical structure of sulfated chitosan obtained by microwave and by conventional technology. FTIR and C-13 NMR spectral analyses demonstrated that a significantly shorter time is required to obtain a satisfactory degree of substitution and molecular weight by microwave radiation than by conventional technology. In this present paper, we also determined antioxidant activity of low-molecular-weight and high-sulfate-content chitosans (LCTS). The results showed LCTS could scavenge superoxide and hydroxyl radical. Its IC50 is 0.025 and 1.32mg/mL, respectively. It is a potential antioxidant in vitro. (C) 2004 Published by Elsevier Ltd. |
| 学科主题 | Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Organic |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000224716400005 |
| 公开日期 | 2010-12-22 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/3575]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 海洋研究所_海洋环境工程技术研究发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xing, RE,Liu, S,Yu, HH,et al. Preparation of low-molecular-weight and high-sulfate-content chitosans under microwave radiation and their potential antioxidant activity in vitro[J]. CARBOHYDRATE RESEARCH,2004,339(15):2515-2519. |
| APA | Xing, RE,Liu, S,Yu, HH,Zhang, QB,Li, Z,&Li, PC.(2004).Preparation of low-molecular-weight and high-sulfate-content chitosans under microwave radiation and their potential antioxidant activity in vitro.CARBOHYDRATE RESEARCH,339(15),2515-2519. |
| MLA | Xing, RE,et al."Preparation of low-molecular-weight and high-sulfate-content chitosans under microwave radiation and their potential antioxidant activity in vitro".CARBOHYDRATE RESEARCH 339.15(2004):2515-2519. |
入库方式： OAI收割
来源：海洋研究所
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