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The chemical constituents from red alga Gymnogongrus flabelliformis Harv.

文献类型：期刊论文

作者Yuan Zhaohui1; Han Lijun1; Su Hua1,4; Shi Dayong1; Sun Jie; Li Shuai2,3; Shi Jiangong2,3
刊名CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
出版日期2008-05-01
卷号26期号:2页码:190-192
关键词Red Algae Gymnogongrus Flabelliformis Harv. Chemical Constituents Mtt Assay
ISSN号0254-4059
DOI10.1007/s00343-008-0190-5
文献子类Article
英文摘要Eight compounds were isolated from red alga Gymnogongrus flabelliformis Harv. In normal phase silica gel, Sephadex LH-20 gel column chromatography, reverse phase HPLC, and recrystallization. Based on MS and 1D NMR spectroscopic data, their structures were determined as: stigmast-4-en-3-one (I), cholest-4-en-3-one (II), cholesterol (III), uracil (IV), uridine (V), adenosine (VI), succinic acid (VII), and 5-hydroxy-4-methyl-5-pentyl-2,5-dihydro-furan-2-on (VIII). All of them were obtained from this species for the first time. Cytotoxicity of these compounds was screened using standard MTT method, but all the compounds were inactive (IC(50) > 10 mu g/ml).; Eight compounds were isolated from red alga Gymnogongrus flabelliformis Harv. In normal phase silica gel, Sephadex LH-20 gel column chromatography, reverse phase HPLC, and recrystallization. Based on MS and 1D NMR spectroscopic data, their structures were determined as: stigmast-4-en-3-one (I), cholest-4-en-3-one (II), cholesterol (III), uracil (IV), uridine (V), adenosine (VI), succinic acid (VII), and 5-hydroxy-4-methyl-5-pentyl-2,5-dihydro-furan-2-on (VIII). All of them were obtained from this species for the first time. Cytotoxicity of these compounds was screened using standard MTT method, but all the compounds were inactive (IC50 > 10 mu g/ml).
学科主题Limnology ; Oceanography
URL标识查看原文
语种英语
WOS记录号WOS:000256416000011
公开日期2010-12-24
源URL[http://ir.qdio.ac.cn/handle/337002/6111]  
专题海洋研究所_海洋生物技术研发中心
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Med Sci, Inst Mat Med, Beijing 10005, Peoples R China
3.Peking Union Med Coll, Beijing 10005, Peoples R China
4.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714		 Yuan Zhaohui,Han Lijun,Su Hua,et al. The chemical constituents from red alga Gymnogongrus flabelliformis Harv.[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2008,26(2):190-192.
APA Yuan Zhaohui.,Han Lijun.,Su Hua.,Shi Dayong.,Sun Jie.,...&Shi Jiangong.(2008).The chemical constituents from red alga Gymnogongrus flabelliformis Harv..CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,26(2),190-192.
MLA Yuan Zhaohui,et al."The chemical constituents from red alga Gymnogongrus flabelliformis Harv.".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 26.2(2008):190-192.

入库方式： OAI收割

来源：海洋研究所

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