A novel method of prediction and optimization for preparative high-performance liquid chromatography separation
文献类型：期刊论文
| 作者 | Jin, Yu1; Xue, Xingya1; Liu, Yanfang1; Xiao, Yuansheng1; Zhang, Jing1; Shi, Hui2; Zhang, Feifang1; Liang, Xinmiao1,2 |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2008-03-07 |
| 卷号 | 1183期号:1-2页码:76-86 |
| 关键词 | prediction optimization preparative high-performance liquid chromatography (preparative HPLC) retention equation complex sample traditional Chinese medicine (TCM) |
| 产权排序 | 1;1 |
| 通讯作者 | 梁鑫淼 |
| 英文摘要 | the preparation of components from a complex sample is a difficult task. the optimization of the separation and subsequent scale-up is usually carried out by trial and error. in this study, the relationship between retention parameters a and c for analytical and preparative separations was developed when the same solid adsorbent and mobile phase were used. the prediction and optimization of the preparative separation of a complex sample could be achieved by direct and simple conversion of the experimentally determined data from an analytical level. the novel method was successfully applied to optimize the separation of target compounds in traditional chinese medicine (tcm). (c) 2008 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | gradient elution ; retention times ; purification ; model |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000253869900009 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/100093]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Grad Sch, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin, Yu,Xue, Xingya,Liu, Yanfang,et al. A novel method of prediction and optimization for preparative high-performance liquid chromatography separation[J]. journal of chromatography a,2008,1183(1-2):76-86. |
| APA | Jin, Yu.,Xue, Xingya.,Liu, Yanfang.,Xiao, Yuansheng.,Zhang, Jing.,...&Liang, Xinmiao.(2008).A novel method of prediction and optimization for preparative high-performance liquid chromatography separation.journal of chromatography a,1183(1-2),76-86. |
| MLA | Jin, Yu,et al."A novel method of prediction and optimization for preparative high-performance liquid chromatography separation".journal of chromatography a 1183.1-2(2008):76-86. |
入库方式： OAI收割
来源：大连化学物理研究所
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