Study on the retention equation in hydrophilic interaction liquid chromatography
文献类型:期刊论文
作者 | Jin, Gaowa; Guo, Zhimou; Zhang, Feifang; Xue, Xingya; Jin, Yu; Liang, Xinmiao |
刊名 | talanta
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出版日期 | 2008-07-30 |
卷号 | 76期号:3页码:522-527 |
关键词 | hydrophilic interaction liquid chromatography retention equation stationary phases selectivity nucleoside |
产权排序 | 1;1 |
通讯作者 | 梁鑫淼 |
英文摘要 | hydrophilic interaction liquid chromatography (hilic) is an effective technique for separating polar compounds. but its retention equation has not been studied systematically yet. in this study, an appropriate retention equation was established by using eight nucleosides as model analytes and by comparing four retention models on six different hilic columns. as a result, retention equation in k = a + b x incb + c x c-b could be quantitatively described the retention factors with good accuracy in hilic mode. based on this equation, the retention times of eight nucleosides under the conditions by other mobile phase can be predicted on each column. all of the predicted relative errors of retention times were smaller than 5%. the established retention model was also successfully applied to predict retention times of the real traditional chinese medicine-carthaus tinctorius l. sample. (c) 2008 elsevier b.v. all rights reserved. |
WOS标题词 | science & technology ; physical sciences |
类目[WOS] | chemistry, analytical |
研究领域[WOS] | chemistry |
关键词[WOS] | electrospray mass-spectrometry ; light-scattering detection ; small polar compounds ; reversed-phase ; adrenoreceptor agonists ; stationary-phase ; drug discovery ; separation ; silica ; performance |
收录类别 | SCI |
原文出处 | true |
语种 | 英语 |
WOS记录号 | WOS:000257577100006 |
公开日期 | 2010-11-30 |
源URL | [http://159.226.238.44/handle/321008/100097] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China |
推荐引用方式 GB/T 7714 | Jin, Gaowa,Guo, Zhimou,Zhang, Feifang,et al. Study on the retention equation in hydrophilic interaction liquid chromatography[J]. talanta,2008,76(3):522-527. |
APA | Jin, Gaowa,Guo, Zhimou,Zhang, Feifang,Xue, Xingya,Jin, Yu,&Liang, Xinmiao.(2008).Study on the retention equation in hydrophilic interaction liquid chromatography.talanta,76(3),522-527. |
MLA | Jin, Gaowa,et al."Study on the retention equation in hydrophilic interaction liquid chromatography".talanta 76.3(2008):522-527. |
入库方式: OAI收割
来源:大连化学物理研究所
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