Systematic screening and characterization of flavonoid glycosides in Carthamus tinctorius L. by liquid chromatography/UV diode-array detection/electrospray ionization tandem mass spectrometry
文献类型：期刊论文
| 作者 | Jin, Yu; Xiao, Yuan-sheng; Zhang, Fei-fang; Xue, Xing-ya; Xu, Qing; Liang, Xin-miao |
| 刊名 | journal of pharmaceutical and biomedical analysis
 |
| 出版日期 | 2008-02-13 |
| 卷号 | 46期号:3页码:418-430 |
| 关键词 | screening characterization flavonoid glycosides Carthamus tinctorius L. HPLC/DAD/ESI-MS" |
| 产权排序 | 1;1 |
| 通讯作者 | 梁鑫淼 |
| 英文摘要 | the traditional chinese medicine (tcm) is a complex system, which always consists of numerous compounds with significant difference in the content and physical and chemical properties. in this paper, a screening method based on target molecular weights was developed to characterize the flavonoid glycosides in the flower of carthamus tinctorius l. the screening tables of aglycone and glycan were designed, respectively, in order to select and combine freely. the multiple reaction monitoring (mrm) scan mode with higher sensitivity and selectivity was adopted in the screening, which benefit the characterization for the minor components. seventy-seven flavonoid glycosides were screened out finally, and their structures were characterized by tandem mass spectrometric method in both positive and negative ion modes. the glycosylation mode, aglycone, sequence and/or the interglycosidic linkages of the glycan portion and glycosylation position were elucidated by the fragmentation rule in the ms. numerous compounds screened out with this method showed the structure variety in secondary plant metabolites, and the purposeful screening systemically and subsequent structure characterization offered more information about the chemical constitutions of tcm. (c) 2007 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences ; life sciences & biomedicine |
| 类目[WOS] | chemistry, analytical ; pharmacology & pharmacy |
| 研究领域[WOS] | chemistry ; pharmacology & pharmacy |
| 关键词[WOS] | electrospray-ionization ; o-glycosides ; differentiation ; identification ; yellow ; aglycones ; safflower ; isomers ; plants ; petals |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000253100400002 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/100099]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Grad Sch, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin, Yu,Xiao, Yuan-sheng,Zhang, Fei-fang,et al. Systematic screening and characterization of flavonoid glycosides in Carthamus tinctorius L. by liquid chromatography/UV diode-array detection/electrospray ionization tandem mass spectrometry[J]. journal of pharmaceutical and biomedical analysis,2008,46(3):418-430. |
| APA | Jin, Yu,Xiao, Yuan-sheng,Zhang, Fei-fang,Xue, Xing-ya,Xu, Qing,&Liang, Xin-miao.(2008).Systematic screening and characterization of flavonoid glycosides in Carthamus tinctorius L. by liquid chromatography/UV diode-array detection/electrospray ionization tandem mass spectrometry.journal of pharmaceutical and biomedical analysis,46(3),418-430. |
| MLA | Jin, Yu,et al."Systematic screening and characterization of flavonoid glycosides in Carthamus tinctorius L. by liquid chromatography/UV diode-array detection/electrospray ionization tandem mass spectrometry".journal of pharmaceutical and biomedical analysis 46.3(2008):418-430. |
入库方式： OAI收割
来源：大连化学物理研究所
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