Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review
文献类型：期刊论文
| 作者 | Wang, Bao-Cheng1,2; Wang, Li-Jun1; Jiang, Bo1; Wang, Shuai-Yu1; Wu, Ning1; Li, Xiang-Qian1; Shi, Da-Yong1,2,3 |
| 刊名 | MINI-REVIEWS IN MEDICINAL CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 17期号:8页码:683-692 |
| 关键词 | Application Of Fluorine Anticancer Antimicrobial Anti-inflammatory Antivirus Activity Drug Design Importance Of Fluorinated Compounds |
| DOI | 10.2174/1389557515666151016124957 |
| 文献子类 | Review |
| 英文摘要 | Background: The widespread application of fluorine in drug design benefits from distinctive properties. Incorporation of fluorine can positively modulate certain pharmacokinetics properties, including lipophilicity, eletrophilicity, metabolic stability, chemical stability, et al., which were of interest to medicinal chemists. Herein, fluorinated compounds, which have been designed and evaluated for anticancer, antimicrobial, anti-inflammatory and antivirus activity, et al. during the last 6 years (2010-2015) are summarized. |
| 语种 | 英语 |
| WOS记录号 | WOS:000402475700005 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/137080]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Bao-Cheng,Wang, Li-Jun,Jiang, Bo,et al. Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2017,17(8):683-692. |
| APA | Wang, Bao-Cheng.,Wang, Li-Jun.,Jiang, Bo.,Wang, Shuai-Yu.,Wu, Ning.,...&Shi, Da-Yong.(2017).Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review.MINI-REVIEWS IN MEDICINAL CHEMISTRY,17(8),683-692. |
| MLA | Wang, Bao-Cheng,et al."Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review".MINI-REVIEWS IN MEDICINAL CHEMISTRY 17.8(2017):683-692. |
入库方式： OAI收割
来源：海洋研究所
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