Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation
文献类型：期刊论文
| 作者 | Li, Kecheng1,2; Xing, Ronge1 ; Liu, Song1; Qin, Yukun1; Li, Pengcheng1
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| 刊名 | BIOMED RESEARCH INTERNATIONAL
 |
| 出版日期 | 2017 |
| DOI | 10.1155/2017/2486515 |
| 文献子类 | Article |
| 英文摘要 | Chitohexaose has attracted wide interest due to its special bioactivities and these potential activities are significantly related to N-acetylation. Herein, six chitohexaose fractions with different degrees of acetylation were prepared by selective N-acetylation and ion-exchange chromatography and further analyzed by ESI/MS. It is revealed that all the six N-acetylated chitohexaoses were of single molecular weight, the molecular weights of which were exactly assigned to 1026.44 Da, 1068.44 Da, 1110.48 Da, 1152.48 Da, 1194.49 Da, and 1236.48 Da, respectively. These results suggested that the six prepared N-acetylated chitohexaoses were N-acetylchitohexaose (D5A1), di-N-acetylchitohexaose (D4A2), tri-N-acetylchitohexaose (D3A3), tetra-N-acetylchitohexaose (D2A4), penta-N-acetylchitohexaose (D1A5), and hexa-N-acetylchitohexaose (A6), respectively, which are of great significance to screen their bioactivities and discover well-defined chitooligosaccharide molecules as potential drugs. |
| 语种 | 英语 |
| WOS记录号 | WOS:000402657100001 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/137099]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.IOCAS, Nantong Marine Sci & Technol R&D Ctr, Nantong 226006, Jiangsu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Kecheng,Xing, Ronge,Liu, Song,et al. Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation[J]. BIOMED RESEARCH INTERNATIONAL,2017. |
| APA | Li, Kecheng,Xing, Ronge,Liu, Song,Qin, Yukun,&Li, Pengcheng.(2017).Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation.BIOMED RESEARCH INTERNATIONAL. |
| MLA | Li, Kecheng,et al."Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation".BIOMED RESEARCH INTERNATIONAL (2017). |
入库方式： OAI收割
来源：海洋研究所
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