In vivo growth-inhibition of S 180 tumor by mixture of 5-Fu and low molecular lambda-carrageenan from Chondrus ocellatus
文献类型：期刊论文
| 作者 | Zhou, GF; Xin, H; Sheng, WX; Sun, YP; Li, Z; Xu, ZH |
| 刊名 | PHARMACOLOGICAL RESEARCH
 |
| 出版日期 | 2005-02-01 |
| 卷号 | 51期号:2页码:153-157 |
| 关键词 | Low Molecular Lambda-carrageenan 5-fu Antitumor Immunocompetence |
| ISSN号 | 1043-6618 |
| DOI | 10.1016/j.phrs.2004.07.003 |
| 文献子类 | Article |
| 英文摘要 | lambda-carrageenan is a sulfated galactan isolated from some red algae and have been reported to have many kinds of biological activities. Chondrus ocellatus is an important economic alga in China and many other parts of the world. The sample was obtained after lambda-carrageenan from the alga was degraded by microwave and its molecular weight is 9.3 kDa. In this study, tumor inhibiting activity of low molecular weight lambda-carrageenan and its mixture with 5-Fu on mice transplanted with S 180 tumor was investigated. Weight of immune organ, proliferation ratio of lymphocyte concentration of TNF-alpha and histopathology of spleen and tumor from the transplanted S 180 tumor mice were also deter-mined. Results indicated that the degraded lambda-carrageenan could enhance antitumor activity of 5-Fu and improve immunocompetence damaged by 5-Fu. (C) 2004 Published by Elsevier Ltd.; POLYSACCHARIDES; ANTICOAGULANT; SURVIVAL |
| 学科主题 | Pharmacology & Pharmacy |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000226559600009 |
| 公开日期 | 2010-12-22 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/3627]  |
| 专题 | 海洋研究所_其他 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Laiyang Agr Coll, Qingdao 266109, Peoples R China 4.Laiyang Hlth Sch, Dept Pathol, Laiyang 265200, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, GF,Xin, H,Sheng, WX,et al. In vivo growth-inhibition of S 180 tumor by mixture of 5-Fu and low molecular lambda-carrageenan from Chondrus ocellatus[J]. PHARMACOLOGICAL RESEARCH,2005,51(2):153-157. |
| APA | Zhou, GF,Xin, H,Sheng, WX,Sun, YP,Li, Z,&Xu, ZH.(2005).In vivo growth-inhibition of S 180 tumor by mixture of 5-Fu and low molecular lambda-carrageenan from Chondrus ocellatus.PHARMACOLOGICAL RESEARCH,51(2),153-157. |
| MLA | Zhou, GF,et al."In vivo growth-inhibition of S 180 tumor by mixture of 5-Fu and low molecular lambda-carrageenan from Chondrus ocellatus".PHARMACOLOGICAL RESEARCH 51.2(2005):153-157. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。