Rhodium(iii)-catalyzed annulation of acetophenone o-acetyl oximes with allenoates through arene c-h activation: an access to isoquinolines
文献类型：期刊论文
| 作者 | Wang, Quannan1,2; Lou, Jiang1,2; Huang, Zilong1,2; Yu, Zhengkun1,3 |
| 刊名 | Journal of organic chemistry
 |
| 出版日期 | 2019-02-15 |
| 卷号 | 84期号:4页码:2083-2092 |
| ISSN号 | 0022-3263 |
| DOI | 10.1021/acs.joc.8b03092 |
| 通讯作者 | Yu, zhengkun(zkyu@dicp.ac.cn) |
| 英文摘要 | Rhodium(iii)-catalyzed annulation of acetophenone o-acetyl oximes with allenoates was achieved, affording isoquinolines in good to excellent yields with high regioselectivities under redox-neutral conditions. allenoates acted as the c2 synthons in the annulation reaction. the present synthetic methodology features good functional group tolerance and avoids metal salts as the external oxidants. the proposed mechanism suggests that the reaction proceeds through arene c-h activation, allene insertion, and c-n coupling. |
| WOS关键词 | REGIOSELECTIVE INTERMOLECULAR ANNULATION ; BOND ACTIVATION ; ASYMMETRIC-SYNTHESIS ; DIRECT ARYLATION ; ALLENES ; FUNCTIONALIZATION ; ALLYLATION ; ALKYNES ; DECARBONYLATION ; SULFONAMIDES |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000459367100041 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2372670 |
| 专题 | 大连化学物理研究所 |
| 通讯作者 | Yu, Zhengkun |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, 457 Zhongshan Rd, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 354 Fenglin Rd, Shanghai 200032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Quannan,Lou, Jiang,Huang, Zilong,et al. Rhodium(iii)-catalyzed annulation of acetophenone o-acetyl oximes with allenoates through arene c-h activation: an access to isoquinolines[J]. Journal of organic chemistry,2019,84(4):2083-2092. |
| APA | Wang, Quannan,Lou, Jiang,Huang, Zilong,&Yu, Zhengkun.(2019).Rhodium(iii)-catalyzed annulation of acetophenone o-acetyl oximes with allenoates through arene c-h activation: an access to isoquinolines.Journal of organic chemistry,84(4),2083-2092. |
| MLA | Wang, Quannan,et al."Rhodium(iii)-catalyzed annulation of acetophenone o-acetyl oximes with allenoates through arene c-h activation: an access to isoquinolines".Journal of organic chemistry 84.4(2019):2083-2092. |
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来源：大连化学物理研究所
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