中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 大连化学物理研究所
[4+1] cycloaddition of enaminothiones and aldehyde n-tosylhydrazones toward 3-aminothiophenes

文献类型：期刊论文

作者Liu, Zhuqing1,2; Wu, Ping1,2; He, Yuan1,2; Yang, Ting1; Yu, Zhengkun1,3
刊名Advanced synthesis & catalysis
出版日期2018-11-16
卷号360期号:22页码:4381-4392
关键词Thiophenes Enaminothiones Hydrazones Cycloaddition 3-aminothiophenes
ISSN号1615-4150
DOI10.1002/adsc.201801028
通讯作者Yu, zhengkun(zkyu@dicp.ac.cn)
英文摘要An efficient protocol toward trisubstituted 3-aminothiophenes has been developed through a [4+1] cycloaddition of enaminothiones and aldehyde n-tosylhydrazones under transition-metal-free conditions. 3-aminothiophene derivatives as well as their chiral analogs were obtained in good to excellent yields. direct interaction of the enaminothiones with the diazo compounds of alpha-carbonyl or ester group-functionalized aldehydes also efficiently afforded the same type of 3-aminothiophenes. the diversity of the synthetic methodology has been demonstrated by the broad substrate scopes and excellent chemoselectivity in cleavage of the c-s, c-o, and c-n bonds in enaminothiones.
WOS关键词ONE-POT SYNTHESIS ; KETENE N,S-ACETALS ; THIOBENZOYLKETENE S,N-ACETALS ; THIOAROYLKETENE S,N-ACETALS ; MEDICINAL CHEMISTRY ; EFFICIENT SYNTHESIS ; DIAZO-COMPOUNDS ; DOMINO REACTION ; GENERAL-METHOD ; THIOPHENES
WOS研究方向Chemistry
WOS类目Chemistry, Applied ; Chemistry, Organic
语种英语
WOS记录号WOS:000450364400015
出版者WILEY-V C H VERLAG GMBH
URI标识http://www.irgrid.ac.cn/handle/1471x/2373108
专题大连化学物理研究所
通讯作者Yu, Zhengkun
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, 457 Zhongshan Rd, Dalian 116023, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, State Key Lab Organometall Chem, Shanghai Inst Organ Chem, 354 Fenglin Rd, Shanghai 200032, Peoples R China
推荐引用方式
GB/T 7714		 Liu, Zhuqing,Wu, Ping,He, Yuan,et al. [4+1] cycloaddition of enaminothiones and aldehyde n-tosylhydrazones toward 3-aminothiophenes[J]. Advanced synthesis & catalysis,2018,360(22):4381-4392.
APA Liu, Zhuqing,Wu, Ping,He, Yuan,Yang, Ting,&Yu, Zhengkun.(2018).[4+1] cycloaddition of enaminothiones and aldehyde n-tosylhydrazones toward 3-aminothiophenes.Advanced synthesis & catalysis,360(22),4381-4392.
MLA Liu, Zhuqing,et al."[4+1] cycloaddition of enaminothiones and aldehyde n-tosylhydrazones toward 3-aminothiophenes".Advanced synthesis & catalysis 360.22(2018):4381-4392.

入库方式： iSwitch采集

来源：大连化学物理研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。