Genome characteristics of the cyclophragma undans nucleopolyhedrovirus: a distinct species in group i of alphabaculovirus
文献类型：期刊论文
| 作者 | Zhu, Zheng1,2; Wang, Jun1,2; Wang, Qianran1,2; Yin, Feifei1,2; Liu, Xiaoping1,2; Hou, Dianhai1,2; Zhang, Lei1,2; Liu, Haizhou1,2; Li, Jiang1,2; Arif, Basil M.3 |
| 刊名 | Virologica sinica
 |
| 出版日期 | 2018-08-01 |
| 卷号 | 33期号:4页码:359-368 |
| 关键词 | Cyclophragma undans nucleopolyhedrovirus (cyunnpv) Baculovirus Group i alphabaculovirus F protein |
| ISSN号 | 1674-0769 |
| DOI | 10.1007/s12250-018-0047-9 |
| 通讯作者 | Wang, manli(wangml@wh.iov.cn) |
| 英文摘要 | The cyclophragma undans nucleopolyhedrovirus (cyunnpv), a potential pest control agent, was isolated from cyclophragma undans (lepidoptera: lasiocampidae), an important forest pest. in the present study, we performed detailed genome analysis of cyunnpv and compared its genome to those of other group i alphabaculoviruses. sequencing of the cyunnpv genome using the roche 454 sequencing system generated 142,900bp with a g+c content of 45%. genome analysis predicted a total of 147 hypothetical open reading frames comprising 38 baculoviral core genes, 24 lepidopteran baculovirus conserved genes, nine group i alphabaculovirus conserved genes, 71 common genes, and five genes that are unique to cyunnpv. in addition, the genome contains 13 homologous repeated sequences (hrs). phylogenetic analysis groups cyunnpv under a distinct branch within clade a of group i in the genus alphabaculovirus. unlike other members of group i, cyunnpv harbors only nine of the 11 genes previously determined to be specific to group i viruses. furthermore, the cyunnpv lacks the tyrosine phosphatase gene and the ac30 gene. the cyunnpv f-like protein contains two insertions of continuous polar amino acids, one at the conventional fusion peptide and a second insertion at the pre-transmembrane domain. the insertions are likely to affect the fusion function and suggest an evolutionary process that led to inactivation of the f-like protein. the above findings imply that cyunnpv is a distinct species under group i alphabaculovirus. |
| WOS关键词 | ENVELOPE FUSION PROTEIN ; NUCLEAR POLYHEDROSIS-VIRUS ; SINGLE-NUCLEOCAPSID NUCLEOPOLYHEDROVIRUS ; BACULOVIRUS-ENCODED PROTEIN ; TYROSINE-PHOSPHATASE ; DNA-REPLICATION ; RNA 5'-TRIPHOSPHATASE ; ORGYIA-PSEUDOTSUGATA ; FUNCTIONAL-ANALYSIS ; F PROTEIN |
| WOS研究方向 | Virology |
| WOS类目 | Virology |
| 语种 | 英语 |
| WOS记录号 | WOS:000444001200007 |
| 出版者 | SPRINGER |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2373245 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Wang, Manli |
| 作者单位 | 1.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Hubei, Peoples R China 2.Chinese Acad Sci, Wuhan Inst Virol, China Ctr Virus Culture Collect, Wuhan 430071, Hubei, Peoples R China 3.Canadian Forest Serv, Great Lakes Forestry Ctr, Sault Ste Marie, ON P6A 2E5, Canada |
| 推荐引用方式 GB/T 7714 | Zhu, Zheng,Wang, Jun,Wang, Qianran,et al. Genome characteristics of the cyclophragma undans nucleopolyhedrovirus: a distinct species in group i of alphabaculovirus[J]. Virologica sinica,2018,33(4):359-368. |
| APA | Zhu, Zheng.,Wang, Jun.,Wang, Qianran.,Yin, Feifei.,Liu, Xiaoping.,...&Wang, Manli.(2018).Genome characteristics of the cyclophragma undans nucleopolyhedrovirus: a distinct species in group i of alphabaculovirus.Virologica sinica,33(4),359-368. |
| MLA | Zhu, Zheng,et al."Genome characteristics of the cyclophragma undans nucleopolyhedrovirus: a distinct species in group i of alphabaculovirus".Virologica sinica 33.4(2018):359-368. |
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来源：武汉病毒研究所
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