Microcalorimetric studies on the antimicrobial actions of different cephalosporins
文献类型：期刊论文
| 作者 | Yang, L. N.1,2; Xu, F.1; Sun, L. X.1; Zhao, Z. B.3; Song, C. G.4 |
| 刊名 | journal of thermal analysis and calorimetry
 |
| 出版日期 | 2008-08-01 |
| 卷号 | 93期号:2页码:417-421 |
| 关键词 | cefazolin sodium cefonicid sodium cephalosporins E. coli DH5 alpha inhibition microcalorimetry |
| 产权排序 | 1;1 |
| 通讯作者 | 徐芬 |
| 英文摘要 | microcalorimetry was applied to study the effect of cephalosporins (cefazolin sodium and cefonicid sodium) on the e. coli growth. the microbial activity was recorded as power-time curves through an ampoule method with a tam air isothermal microcalorimeter at 37 degrees c. the parameters such as the growth rate constant (k), inhibitory ratio (i), the maximum power output (p-m) and the time corresponding to the maximum power output (t(m)) were calculated. the change tendencies of k, with the increasing of concentration (c) of the two cephalosporins, are similar which show that cefazolin sodium and cefonicid sodium have the same inhibitory mechanism. the experimental results reveal that cefonicid sodium has a stronger antibacterial activity towards e. coli than that of cefazolin sodium and this was coincide with the clinical manifestations. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical ; chemistry, physical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | escherichia-coli dh5-alpha ; in-vitro ; cefazolin sodium ; drug-delivery ; growth ; antibiotics ; metabolism |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000258500000012 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/100353]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Mat & Thermochem Lab, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China 4.Dalian Inst Drug Detect, Dalian 116021, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, L. N.,Xu, F.,Sun, L. X.,et al. Microcalorimetric studies on the antimicrobial actions of different cephalosporins[J]. journal of thermal analysis and calorimetry,2008,93(2):417-421. |
| APA | Yang, L. N.,Xu, F.,Sun, L. X.,Zhao, Z. B.,&Song, C. G..(2008).Microcalorimetric studies on the antimicrobial actions of different cephalosporins.journal of thermal analysis and calorimetry,93(2),417-421. |
| MLA | Yang, L. N.,et al."Microcalorimetric studies on the antimicrobial actions of different cephalosporins".journal of thermal analysis and calorimetry 93.2(2008):417-421. |
入库方式： OAI收割
来源：大连化学物理研究所
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