Drug-induced pseudoallergy: a review of the causes and mechanisms
文献类型：期刊论文
| 作者 | Zhang, Bo; Li, Qin; Shi, Chenyang; Zhang, Xinyue |
| 刊名 | Pharmacology
 |
| 出版日期 | 2018 |
| 卷号 | 101期号:1-2页码:104-110 |
| 关键词 | Complement Drugs Mast cells Pseudoallergy |
| ISSN号 | 0031-7012 |
| DOI | 10.1159/000479878 |
| 通讯作者 | Zhang, xinyue(zhangxy2003@aliyun.com) |
| 英文摘要 | Adverse drug reactions occur frequently and can trigger pseudoallergy, which has become a serious threat to public health. pseudoallergy is a typical non-immune anaphylactic reaction characterized by the independence of antigen-specific immune responses. in the clinic, pseudoallergy is often elicited by the first dose of medication, and here lies its unpredictability and occasional lethal outcome. however, the mechanisms of pseudoallergy are not well understood. this review focusses on the causes and mechanisms of pseudoallergy induced by drugs. two categories of mechanisms will be considered, namely, (1) complement activation-related pseudoallergy and (2) mast cell activation-related pseudoallergy. the factors that induce pseudoallergy include opioid drugs, complement activation-related pseudoallergenic drugs, nonsteroidal anti-inflammatory drugs and traditional chinese medicine injections. (c) 2017 s. karger ag, basel |
| WOS关键词 | ACTIVATION-RELATED PSEUDOALLERGY ; HUMAN MAST-CELLS ; ANAPHYLACTOID REACTION ; HYPERSENSITIVITY REACTIONS ; DEPENDENT ACTIVATION ; BEAGLE DOGS ; COMPLEMENT ; RECEPTORS ; PROTEIN ; INJECTION |
| WOS研究方向 | Pharmacology & Pharmacy |
| WOS类目 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000418642900014 |
| 出版者 | KARGER |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2373307 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Zhang, Xinyue |
| 作者单位 | Zhejiang Acad Med Sci, Inst Mat Med, Dept Pharmacol, Hangzhou 310013, Zhejiang, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Bo,Li, Qin,Shi, Chenyang,et al. Drug-induced pseudoallergy: a review of the causes and mechanisms[J]. Pharmacology,2018,101(1-2):104-110. |
| APA | Zhang, Bo,Li, Qin,Shi, Chenyang,&Zhang, Xinyue.(2018).Drug-induced pseudoallergy: a review of the causes and mechanisms.Pharmacology,101(1-2),104-110. |
| MLA | Zhang, Bo,et al."Drug-induced pseudoallergy: a review of the causes and mechanisms".Pharmacology 101.1-2(2018):104-110. |
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来源：武汉病毒研究所
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