Regulator degu is required for multicellular behavior in lysinibacillus sphaericus
文献类型：期刊论文
| 作者 | Hu, Yimin1,2; Cai, Quanxin1; Tian, Shen1; Ge, Yong1; Yuan, Zhiming1; Hu, Xiaomin1 |
| 刊名 | Research in microbiology
 |
| 出版日期 | 2018-04-01 |
| 卷号 | 169期号:3页码:177-187 |
| 关键词 | Lysinibacillus sphaericus Mosquitocidal Sporulation Degu Spo0a |
| ISSN号 | 0923-2508 |
| DOI | 10.1016/j.resmic.2017.12.006 |
| 通讯作者 | Yuan, zhiming(yzm@wh.iov.cn) ; Hu, xiaomin(huxm@wh.iov.cn) |
| 英文摘要 | Degs and degu make up a two component system belonging to a class of signal transduction systems that play important roles in a broad range of bacterial responses to the environment. however, little study has been done to explore the physiological functions of degs-degu in mosquitocidal lysinibacillus sphaericus. in this study, it was found that deletion of degu or degs-degu inhibited the swarming motility, biofilm formation, sporulation and binary toxin production through regulating the related genes, and phosphorylation was necessary for the functions of degu. based on the findings, a regulation network mediated by degu was delineated. both degu-pi and spo0a-pi positively regulates genes which are linked with the transition from stage. to the end of the sporulation process and also influences the production of binary toxins via regulation on sige. both degu-pi and spo0a-pi negatively regulate abrb/ sinr and influence the biofilm formation. degu-pi can positively regulate the motility via the regulation on sigd. whether the regulations are directly or indirectly need to be explored. moreover, spo0a-pi may indirectly regulate the swarming motility through negatively regulating degu. it was concluded that degu is a global transcriptional regulator on cell swarming motility, biofilm formation, sporulation and virulence in l. sphaericus. (c) 2018 institut pasteur. published by elsevier masson sas. all rights reserved. |
| WOS关键词 | CELL-SPECIFIC TRANSCRIPTION ; BACILLUS-SUBTILIS ; BIOFILM FORMATION ; ACETYL PHOSPHATE ; SPORULATION ; EXPRESSION ; PROTEIN ; GENES ; ACTIVATION ; EXOSPORIUM |
| WOS研究方向 | Microbiology |
| WOS类目 | Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000429413600006 |
| 出版者 | ELSEVIER SCIENCE BV |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2373327 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Yuan, Zhiming; Hu, Xiaomin |
| 作者单位 | 1.Chinese Acad Sci, Wuhan Inst Virol, Wuhan 430070, Hubei, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Yimin,Cai, Quanxin,Tian, Shen,et al. Regulator degu is required for multicellular behavior in lysinibacillus sphaericus[J]. Research in microbiology,2018,169(3):177-187. |
| APA | Hu, Yimin,Cai, Quanxin,Tian, Shen,Ge, Yong,Yuan, Zhiming,&Hu, Xiaomin.(2018).Regulator degu is required for multicellular behavior in lysinibacillus sphaericus.Research in microbiology,169(3),177-187. |
| MLA | Hu, Yimin,et al."Regulator degu is required for multicellular behavior in lysinibacillus sphaericus".Research in microbiology 169.3(2018):177-187. |
入库方式： iSwitch采集
来源：武汉病毒研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。