Genome analysis of a novel group i alphabaculovirus obtained from oxyplax ochracea
文献类型：期刊论文
| 作者 | Wang, Jun1; Hou, Dianhai1,2; Wang, Qianran1; Kuang, Wenhua1; Zhang, Lei1; Li, Jiang1; Shen, Shu1; Deng, Fei1; Wang, Hualin1; Hu, Zhihong1 |
| 刊名 | Plos one
 |
| 出版日期 | 2018-02-01 |
| 卷号 | 13期号:2页码:16 |
| ISSN号 | 1932-6203 |
| DOI | 10.1371/journal.pone.0192279 |
| 通讯作者 | Wang, manli(wangml@wh.iov.cn) |
| 英文摘要 | Oxyplax ochracea (moore) is a pest that causes severe damage to a wide range of crops, forests and fruit trees. the complete genome sequence of oxyplax ochracea nucleopolyhedrovirus (oxocnpv) was determined using a roche 454 pyrosequencing system. oxocnpv has a double-stranded dna (dsdna) genome of 113,971 bp with a g+c content of 31.1%. one hundred and twenty-four putative open reading frames (orfs) encoding proteins of >50 amino acids in length and with minimal overlapping were predicted, which covered 92% of the whole genome. six baculoviral typical homologous regions (hrs) were identified. phylogenetic analysis and gene parity plot analysis showed that oxocnpv belongs to clade "a" of group i alphabaculoviruses, and it seems to be close to the most recent common ancestor of group i alphabaculoviruses. three unique orfs (with no homologs in the national center for biotechnology information database) were identified. interestingly, oxocnpv lacks three auxiliary genes (lef7, ie-2 and pcna) related to viral dna replication and rna transcription. in addition, oxocnpv has significantly different sequences for several genes (including ie1 and odv-e66) in comparison with those of other baculoviruses. however, three dimensional structure prediction showed that oxocnpv odv-e66 contain the conserved catalytic residues, implying that it might possess polysaccharide lyase activity as acmnpv odv-e66. all these unique features suggest that oxocnpv represents a novel species of the group i alphabaculovirus lineage. |
| WOS关键词 | NUCLEAR POLYHEDROSIS-VIRUS ; PER-OS INFECTIVITY ; ENVELOPE FUSION PROTEIN ; OCCLUSION-DERIVED VIRUS ; EXPRESSION FACTOR GENES ; DNA-REPLICATION ; NUCLEOCAPSID NUCLEOPOLYHEDROVIRUS ; HOMOLOGOUS DNA ; BOMBYX-MORI ; CELL-LINES |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| 语种 | 英语 |
| 出版者 | PUBLIC LIBRARY SCIENCE |
| WOS记录号 | WOS:000423793400086 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2373340 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Wang, Manli |
| 作者单位 | 1.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan, Hubei, Peoples R China 2.Weifang Med Univ, Sch Biosci & Technol, Weifang, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jun,Hou, Dianhai,Wang, Qianran,et al. Genome analysis of a novel group i alphabaculovirus obtained from oxyplax ochracea[J]. Plos one,2018,13(2):16. |
| APA | Wang, Jun.,Hou, Dianhai.,Wang, Qianran.,Kuang, Wenhua.,Zhang, Lei.,...&Wang, Manli.(2018).Genome analysis of a novel group i alphabaculovirus obtained from oxyplax ochracea.Plos one,13(2),16. |
| MLA | Wang, Jun,et al."Genome analysis of a novel group i alphabaculovirus obtained from oxyplax ochracea".Plos one 13.2(2018):16. |
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来源：武汉病毒研究所
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