A new strain of crimean-congo hemorrhagic fever virus isolated from xinjiang, china
文献类型：期刊论文
| 作者 | Guo, Rong1; Shen, Shu2; Zhang, Yanfang2; Shi, Junming2; Su, Zhengyuan2; Liu, Dan3; Liu, Jinliang2; Yang, Juan2; Wang, Qiguo1; Hu, Zhihong1 |
| 刊名 | Virologica sinica
 |
| 出版日期 | 2017-02-01 |
| 卷号 | 32期号:1页码:80-88 |
| 关键词 | Crimean-congo hemorrhagic fever virus (cchfv) Newborn mice Genotype Phylogenetic analysis |
| ISSN号 | 1674-0769 |
| DOI | 10.1007/s12250-016-3936-9 |
| 通讯作者 | Zhang, yujiang(xjsyzhang@163.com) ; Deng, fei(df@wh.iov.cn) |
| 英文摘要 | Crimean-congo hemorrhagic fever virus (cchfv) is a highly pathogenic tick-borne virus with a fatality rate of up to 50% in humans. cchfv is widely distributed in countries around the world. outbreaks of cchfv infection in humans have occurred in prior years in xinjiang province, china. epidemiological surveys have detected cchfv rna in ticks and animals; however, few isolates were identified. in this study, we identified and isolated a new cchfv strain from hyalomma asiaticum asiaticum ticks collected from north of tarim basin in xinjiang, china. a preliminary investigation of infection and antigens expression of cchfv was performed in newborn mice. the target tissues for cchfv replication in newborn mice were identified. the analysis of the phylogenetic relationships with other chinese strains suggested that diverse genotypes of cchfv have circulated in xinjiang for years. these findings provide important insights into our understanding of cchfv infection and evolution as well as disease prevention and control for local residents. |
| WOS关键词 | REASSORTMENT ; EVOLUTION |
| WOS研究方向 | Virology |
| WOS类目 | Virology |
| 语种 | 英语 |
| WOS记录号 | WOS:000396155400010 |
| 出版者 | SPRINGER |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2373451 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Zhang, Yujiang; Deng, Fei |
| 作者单位 | 1.Ctr Dis Control & Prevent Xinjiang Uygur Autonomo, Urumqi 830002, Xinjiang, Peoples R China 2.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China 3.Wuhan Univ Sci & Technol, Sch Med, Wuhan 430065, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo, Rong,Shen, Shu,Zhang, Yanfang,et al. A new strain of crimean-congo hemorrhagic fever virus isolated from xinjiang, china[J]. Virologica sinica,2017,32(1):80-88. |
| APA | Guo, Rong.,Shen, Shu.,Zhang, Yanfang.,Shi, Junming.,Su, Zhengyuan.,...&Deng, Fei.(2017).A new strain of crimean-congo hemorrhagic fever virus isolated from xinjiang, china.Virologica sinica,32(1),80-88. |
| MLA | Guo, Rong,et al."A new strain of crimean-congo hemorrhagic fever virus isolated from xinjiang, china".Virologica sinica 32.1(2017):80-88. |
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来源：武汉病毒研究所
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