Genesis, evolution and prevalence of h5n6 avian influenza viruses in china
文献类型：期刊论文
| 作者 | Bi, Yuhai1,2,3; Chen, Quanjiao2,4; Wang, Qianli2,3; Chen, Jianjun2,4; Jin, Tao5; Wong, Gary3; Quan, Chuansong6; Liu, Jun6; Wu, Jun2,3; Yin, Renfu7 |
| 刊名 | Cell host & microbe
 |
| 出版日期 | 2016-12-14 |
| 卷号 | 20期号:6页码:810-821 |
| ISSN号 | 1931-3128 |
| DOI | 10.1016/j.chom.2016.10.022 |
| 通讯作者 | Liu, yingxia(yingxialiu@hotmail.com) ; Shi, weifeng(shiwf@ioz.ac.cn) ; Liu, di(liud@im.ac.cn) ; Gao, george fu(gaof@im.ac.cn) |
| 英文摘要 | Constant surveillance of live poultry markets (lpms) is currently the best way to predict and identify emerging avian influenza viruses (aivs) that pose a potential threat to public health. through surveillance of lpms from 16 provinces and municipalities in china during 2014-2016, we identified 3,174 aiv-positive samples and isolated and sequenced 1,135 aivs covering 31 subtypes. our analysis shows that h5n6 has replaced h5n1 as one of the dominant aiv subtypes in southern china, especially in ducks. phylogenetic analysis reveals that h5n6 arose from reassortments of h5 and h6n6 viruses, with the hemagglutinin and neuraminidase combinations being strongly lineage specific. h5n6 viruses constitute at least 34 distinct genotypes derived from various evolutionary pathways. notably, genotype g1.2 virus, with internal genes from the chicken h9n2/h7n9 gene pool, was responsible for at least five human h5n6 infections. our findings highlight h5n6 aivs as potential threats to public health and agriculture. |
| WOS关键词 | LIVE POULTRY MARKETS ; SHORT READ ALIGNMENT ; MIGRATORY BIRDS ; HUMAN INFECTION ; A VIRUSES ; A(H5N6) VIRUS ; H7N9 VIRUS ; HONG-KONG ; ORIGIN ; H9N2 |
| WOS研究方向 | Microbiology ; Parasitology ; Virology |
| WOS类目 | Microbiology ; Parasitology ; Virology |
| 语种 | 英语 |
| 出版者 | CELL PRESS |
| WOS记录号 | WOS:000392843500016 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2373476 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Liu, Yingxia; Shi, Weifeng; Liu, Di; Gao, George Fu |
| 作者单位 | 1.Shenzhen Third Peoples Hosp, State Key Discipline Infect Dis, Shenzhen Key Lab Pathogen & Immun, Shenzhen 518112, Peoples R China 2.Chinese Acad Sci, Ctr Influenza Res & Early Warning CASCIRE, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Inst Microbiol, Collaborat Innovat Ctr Diag & Treatment Infect Di, CAS Key Lab Pathogen Microbiol & Immunol, Beijing 100101, Peoples R China 4.Chinese Acad Sci, Wuhan Inst Virol, CAS Key Lab Special Pathogens & Biosafety, Wuhan 430071, Hubei, Peoples R China 5.BGI Shenzhen, China Natl Genebank Shenzhen, Shenzhen 518083, Peoples R China 6.Chinese Ctr Dis Control & Prevent China CDC, Natl Inst Viral Dis Control & Prevent, Beijing 102206, Peoples R China 7.Jilin Univ, Coll Vet Med, Dept Vet Prevent Med, Changchun 130062, Jilin, Peoples R China 8.Yunnan Ctr Dis Control & Prevent, Kunming 650022, Peoples R China 9.Diqing Tibetan Autonomous Prefecture Ctr Dis Cont, Shangri La 674400, Peoples R China 10.Natl Res Ctr Vet Med, Luoyang 471003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bi, Yuhai,Chen, Quanjiao,Wang, Qianli,et al. Genesis, evolution and prevalence of h5n6 avian influenza viruses in china[J]. Cell host & microbe,2016,20(6):810-821. |
| APA | Bi, Yuhai.,Chen, Quanjiao.,Wang, Qianli.,Chen, Jianjun.,Jin, Tao.,...&Gao, George Fu.(2016).Genesis, evolution and prevalence of h5n6 avian influenza viruses in china.Cell host & microbe,20(6),810-821. |
| MLA | Bi, Yuhai,et al."Genesis, evolution and prevalence of h5n6 avian influenza viruses in china".Cell host & microbe 20.6(2016):810-821. |
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来源：武汉病毒研究所
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