Interferon tau affects mouse intestinal microbiota and expression of il-17
文献类型：期刊论文
| 作者 | Ren, Wenkai1,2; Chen, Shuai1; Zhang, Liwen3; Liu, Gang1; Hussain, Tarique1; Hao, Xiao1; Yin, Jie1; Duan, Jielin1; Tan, Bie1; Wu, Guoyao4 |
| 刊名 | Mediators of inflammation
 |
| 出版日期 | 2016 |
| 页码 | 9 |
| ISSN号 | 0962-9351 |
| DOI | 10.1155/2016/2839232 |
| 通讯作者 | Tan, bie(bietan@isa.ac.cn) ; Yin, yulong(yinyulong@isa.ac.cn) |
| 英文摘要 | This study was conducted to explore the effects of interferon tau (ifnt) on the intestinal microbiota and expression of interleukin 17 (il-17) in the intestine of mice. ifnt supplementation increased microbial diversity in the jejunum and ileum but decreased microbial diversity in the feces. ifnt supplementation influenced the composition of the intestinal microbiota as follows: (1) decreasing the percentage of firmicutes and increasing bacteroidetes in the jejunum and ileum; (2) enhancing the percentage of firmicutes but decreasing bacteroidetes in the colon and feces; (3) decreasing lactobacillus in the jejunum and ileum; (4) increasing the percentage of blautia, bacteroides, alloprevotella, and lactobacillus in the colon; and (5) increasing the percentage of lactobacillus, bacteroides, and allobaculum, while decreasing blautia in the feces. also, ifnt supplementation decreased the expression of il-17 in the intestines of normal mice and of an intestinal pathogen infected mice. in conclusion, ifnt supplementation modulates the intestinal microbiota and intestinal il-17 expression, indicating the applicability of ifnt to treat the intestinal diseases involving il-17 expression and microbiota. |
| WOS关键词 | PREGNANCY RECOGNITION HORMONE ; GUT MICROBIOTA ; AUTOIMMUNE ENCEPHALOMYELITIS ; INNATE IMMUNITY ; I INTERFERONS ; CELLS ; DIFFERENTIATION ; INFLAMMATION ; BALANCE ; OBESITY |
| WOS研究方向 | Cell Biology ; Immunology |
| WOS类目 | Cell Biology ; Immunology |
| 语种 | 英语 |
| WOS记录号 | WOS:000382062000001 |
| 出版者 | HINDAWI PUBLISHING CORP |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2374389 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Tan, Bie; Yin, Yulong |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Agroecol Proc Subtrop Reg, Observat & Expt Stn Anim Nutr & Feed Sci South Ce, Inst Subtrop Agr,Minist Agr,Hunan Prov Engn Res C, Changsha 410125, Hunan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 10008, Peoples R China 3.Jinan First Peoples Hosp, Jinan 250011, Shandong, Peoples R China 4.Texas A&M Univ, Dept Anim Sci, 2471 TAMU, College Stn, TX 77843 USA |
| 推荐引用方式 GB/T 7714 | Ren, Wenkai,Chen, Shuai,Zhang, Liwen,et al. Interferon tau affects mouse intestinal microbiota and expression of il-17[J]. Mediators of inflammation,2016:9. |
| APA | Ren, Wenkai.,Chen, Shuai.,Zhang, Liwen.,Liu, Gang.,Hussain, Tarique.,...&Yin, Yulong.(2016).Interferon tau affects mouse intestinal microbiota and expression of il-17.Mediators of inflammation,9. |
| MLA | Ren, Wenkai,et al."Interferon tau affects mouse intestinal microbiota and expression of il-17".Mediators of inflammation (2016):9. |
入库方式： iSwitch采集
来源：中国科学院大学
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。