Exposure of elf-emf and rf-emf increase the rate of glucose transport and tca cycle in budding yeast
文献类型：期刊论文
| 作者 | Lin, Kang-Wei1,2; Yang, Chuan-Jun1; Lian, Hui-Yong1; Cai, Peng1 |
| 刊名 | Frontiers in microbiology
 |
| 出版日期 | 2016-08-31 |
| 卷号 | 7页码:15 |
| 关键词 | Elf-emf Rf-emf Tca Yeast Glucose transportation |
| ISSN号 | 1664-302X |
| DOI | 10.3389/fmicb.2016.01378 |
| 通讯作者 | Lian, hui-yong(hylian@iue.ac.cn) ; Cai, peng(pcai@iue.ac.cn) |
| 英文摘要 | In this study, we investigated the transcriptional response to 50 hz extremely low frequency electromagnetic field (elf-emf) and 2.0 ghz radio frequency electromagnetic field (rf-emf) exposure by illumine sequencing technology using budding yeast as the model organism. the transcription levels of 28 genes were upregulated and those of four genes were downregulated under elf-emf exposure, while the transcription levels of 29 genes were upregulated and those of 24 genes were downregulated under rf-emf exposure. after validation by reverse transcription quantitative polymerase chain reaction (rt-qpcr), a concordant direction of change both in differential gene expression (dge) and rt-qpcr was demonstrated for nine genes under elf-emf exposure and for 10 genes under rf-emf exposure. the rt-qpcr results revealed that elf-emf and rf-emf exposure can upregulate the expression of genes involved in glucose transportation and the tricarboxylic acid (tca) cycle, but not the glycolysis pathway. energy metabolism is closely related with the cell response to environmental stress including emf exposure. our findings may throw light on the mechanism underlying the biological effects of emf. |
| WOS关键词 | FREQUENCY ELECTROMAGNETIC-FIELDS ; GENE-EXPRESSION ; SACCHAROMYCES-CEREVISIAE ; OXIDATIVE STRESS ; ENERGY-METABOLISM ; GLYOXYLATE CYCLE ; CELLS ; CANCER ; MECHANISMS ; RESISTANCE |
| WOS研究方向 | Microbiology |
| WOS类目 | Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000382268100002 |
| 出版者 | FRONTIERS MEDIA SA |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2374406 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Lian, Hui-Yong; Cai, Peng |
| 作者单位 | 1.Chinese Acad Sci, Inst Urban Environm, Key Lab Urban Environm & Hlth, Phys Environm Grp, Xiamen, Peoples R China 2.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, Kang-Wei,Yang, Chuan-Jun,Lian, Hui-Yong,et al. Exposure of elf-emf and rf-emf increase the rate of glucose transport and tca cycle in budding yeast[J]. Frontiers in microbiology,2016,7:15. |
| APA | Lin, Kang-Wei,Yang, Chuan-Jun,Lian, Hui-Yong,&Cai, Peng.(2016).Exposure of elf-emf and rf-emf increase the rate of glucose transport and tca cycle in budding yeast.Frontiers in microbiology,7,15. |
| MLA | Lin, Kang-Wei,et al."Exposure of elf-emf and rf-emf increase the rate of glucose transport and tca cycle in budding yeast".Frontiers in microbiology 7(2016):15. |
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来源：中国科学院大学
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