Development of portable device for point-of-care testing of tumor marker
文献类型：期刊论文
| 作者 | Fan Yan1,2,3; Wang Yang1,2; Liu Jun-Tao1,2; Luo Jin-Ping1,2; Xu Hui-Ren1,2; Xu Sheng-Wei1,2; Cai Xin-Xia1,2 |
| 刊名 | Chinese journal of analytical chemistry
 |
| 出版日期 | 2016-07-01 |
| 卷号 | 44期号:7页码:1148-1153 |
| 关键词 | Carcinoembryonic antigen Electrochemical detection Differential pulse voltammetry Portable Point-of-care testing |
| ISSN号 | 0253-3820 |
| DOI | 10.1016/s1872-2040(16)60947-7 |
| 通讯作者 | Cai xin-xia(xxcai@mail.ie.ac.cn) |
| 英文摘要 | By combining electrochemical detection technique and electronic technique, a portable device which adopted differential pulse voltammetry (dpv) measurement was developed to meet the needs of high sensitivity and on-site rapid detection of tumor marker. the voltage and current resolution of portable device were 0.8 mv and 1 na, respectively. combined with home-made microfluidic paper-based analytical device, carcinoembryonic antigen (cea) was detected by portable device. experimental results revealed that the dpv peak currents showed good linear relationship with the logarithm of cea concentration in the range of 1-500 mu g l-1. the corresponding correlation coefficient was 0.998 and the limit of detection was 10 ng l-1. according to the principle of specific binding of antibody and antigen with electrochemical detection, cea concentration could be calculated automatically according to the linear equation. the portable device with the features of high sensitivity and low detection limit could be widely used in the point-of-care testing of tumor marker. |
| WOS关键词 | CARCINOEMBRYONIC ANTIGEN ; IMMUNOSENSOR ; DIAGNOSIS |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Analytical |
| 语种 | 英语 |
| WOS记录号 | WOS:000380762100007 |
| 出版者 | ELSEVIER SCIENCE INC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2374466 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Cai Xin-Xia |
| 作者单位 | 1.Chinese Acad Sci, Inst Elect, State Key Lab Transducer Technol, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 10090, Peoples R China 3.Tangshan Univ, Intelligence & Informat Engn Coll, Tangshan 063000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fan Yan,Wang Yang,Liu Jun-Tao,et al. Development of portable device for point-of-care testing of tumor marker[J]. Chinese journal of analytical chemistry,2016,44(7):1148-1153. |
| APA | Fan Yan.,Wang Yang.,Liu Jun-Tao.,Luo Jin-Ping.,Xu Hui-Ren.,...&Cai Xin-Xia.(2016).Development of portable device for point-of-care testing of tumor marker.Chinese journal of analytical chemistry,44(7),1148-1153. |
| MLA | Fan Yan,et al."Development of portable device for point-of-care testing of tumor marker".Chinese journal of analytical chemistry 44.7(2016):1148-1153. |
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来源：中国科学院大学
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