An oxidant-free strategy for indole synthesis via intramolecular c-c bond construction under visible light irradiation: cross-coupling hydrogen evolution reaction
文献类型：期刊论文
| 作者 | Wu, Cheng-Juan; Meng, Qing-Yuan; Lei, Tao; Zhong, Jian-Ji; Liu, Wen-Qiang; Zhao, Lei-Min; Li, Zhi-Jun; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu1 |
| 刊名 | Acs catalysis
 |
| 出版日期 | 2016-07-01 |
| 卷号 | 6期号:7页码:4635-4639 |
| 关键词 | C-h functionalization Indoles Radical addition Cross-coupling hydrogen evolution Photochemistry |
| ISSN号 | 2155-5435 |
| DOI | 10.1021/acscatal.6b00917 |
| 通讯作者 | Wu, li-zhu(lzwu@mail.ipc.ac.cn) |
| 英文摘要 | We describe here an oxidant-free strategy to synthesize indoles, i.e., under visible-light irradiation (lambda = 450 nm), catalytic amounts of an iridium(iii) photosensitizer and cobaloxime catalyst transform various n-aryl enamines exclusively into indoles. our methodology affords indoles in good to excellent yields under mild reaction conditions and produces h-2 as the only byproduct. spectroscopic and electrochemical studies verify that the designed system proceeds via visible-light-catalyzed oxidation of n-aryl enamines, followed by intramolecular radical addition to yield the indoles smoothly under ambient conditions. |
| WOS关键词 | N-ARYL ENAMINES ; NONREARRANGED MONOTERPENOID UNIT ; CATALYZED CASCADE PROCESS ; H ACTIVATION ; OXIDATIVE CYCLIZATION ; STYRYL AZIDES ; HOMOGENEOUS SYSTEM ; NOBLE-METALS ; FUNCTIONALIZATION ; ALKYNES |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Physical |
| 语种 | 英语 |
| WOS记录号 | WOS:000379457300069 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2374740 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Wu, Li-Zhu |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Photochem Convers & Optoelect Mat, Tech Inst Phys & Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Chinese Acad Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Cheng-Juan,Meng, Qing-Yuan,Lei, Tao,et al. An oxidant-free strategy for indole synthesis via intramolecular c-c bond construction under visible light irradiation: cross-coupling hydrogen evolution reaction[J]. Acs catalysis,2016,6(7):4635-4639. |
| APA | Wu, Cheng-Juan.,Meng, Qing-Yuan.,Lei, Tao.,Zhong, Jian-Ji.,Liu, Wen-Qiang.,...&Wu, Li-Zhu.(2016).An oxidant-free strategy for indole synthesis via intramolecular c-c bond construction under visible light irradiation: cross-coupling hydrogen evolution reaction.Acs catalysis,6(7),4635-4639. |
| MLA | Wu, Cheng-Juan,et al."An oxidant-free strategy for indole synthesis via intramolecular c-c bond construction under visible light irradiation: cross-coupling hydrogen evolution reaction".Acs catalysis 6.7(2016):4635-4639. |
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来源：中国科学院大学
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