Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation
文献类型：期刊论文
| 作者 | Lei, Jie1,2,3; Xu, Zhi-Gang3; Li, Shi-Qiang3; Xu, Jia3; Zhu, Jin2,3; Chen, Zhong-Zhu3 |
| 刊名 | Molecular diversity
 |
| 出版日期 | 2016-11-01 |
| 卷号 | 20期号:4页码:859-865 |
| 关键词 | Cyclization Heterocycles Ugi-type multicomponent reactions Udc strategy Intramolecular amidation One-pot procedure Mcrs |
| ISSN号 | 1381-1991 |
| DOI | 10.1007/s11030-016-9679-6 |
| 通讯作者 | Xu, zhi-gang(xuzhigangyours@yahoo.com) ; Chen, zhong-zhu(18883138277@163.com) |
| 英文摘要 | Four series of heterocyclic compounds were obtained using ugi-type multicomponent reactions (mcrs) with methyl 2-formylbenzoate as one of the starting materials. a facile and efficient one-pot procedure was suitable for all the mcrs under acidic conditions. this process provided access to four series of complex and potentially biologically active scaffolds. |
| WOS关键词 | MOLECULAR DIVERSITY ; DRUG DISCOVERY ; ONE-POT ; ISOCYANIDES ; CHEMISTRY ; STRATEGY ; BENZIMIDAZOLES ; CONDENSATION ; CHEMOTYPES ; TETRAZOLES |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy |
| WOS类目 | Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Medicinal ; Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000385192900007 |
| 出版者 | SPRINGER |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2374822 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Xu, Zhi-Gang; Chen, Zhong-Zhu |
| 作者单位 | 1.Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chiral Technol Sichuan P, Chengdu 610041, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chongqing Univ Arts & Sci, Chongqing Engn Lab Targeted & Innovat Therapeut, Chongqing Key Lab Kinase Modulators Innovat Med, IATTI, 319 Honghe Ave, Chongqing 402160, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lei, Jie,Xu, Zhi-Gang,Li, Shi-Qiang,et al. Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation[J]. Molecular diversity,2016,20(4):859-865. |
| APA | Lei, Jie,Xu, Zhi-Gang,Li, Shi-Qiang,Xu, Jia,Zhu, Jin,&Chen, Zhong-Zhu.(2016).Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation.Molecular diversity,20(4),859-865. |
| MLA | Lei, Jie,et al."Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation".Molecular diversity 20.4(2016):859-865. |
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来源：中国科学院大学
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